node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C10orf55 | DCAF7 | ENSP00000409225 | ENSP00000483236 | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | DDB1- and CUL4-associated factor 7; Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4- DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat DCAF7 family | 0.445 |
C10orf55 | DUS3L | ENSP00000409225 | ENSP00000311977 | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | 0.530 |
C10orf55 | ERCC4 | ENSP00000409225 | ENSP00000310520 | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | DNA repair endonuclease XPF; Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link; Belongs to the XPF family | 0.540 |
C10orf55 | GRSF1 | ENSP00000409225 | ENSP00000254799 | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | G-rich sequence factor 1; Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences | 0.435 |
C10orf55 | MYADM | ENSP00000409225 | ENSP00000375649 | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | Myeloid associated differentiation marker; Belongs to the MAL family | 0.489 |
C10orf55 | RABEPK | ENSP00000409225 | ENSP00000362639 | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport | 0.556 |
C10orf55 | SHPK | ENSP00000409225 | ENSP00000225519 | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | Sedoheptulokinase; Acts as a modulator of macrophage activation through control of glucose metabolism | 0.513 |
C10orf55 | TMEM56 | ENSP00000409225 | ENSP00000359222 | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | Transmembrane protein 56; TLC domain containing | 0.541 |
DCAF7 | C10orf55 | ENSP00000483236 | ENSP00000409225 | DDB1- and CUL4-associated factor 7; Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4- DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat DCAF7 family | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | 0.445 |
DUS3L | C10orf55 | ENSP00000311977 | ENSP00000409225 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | 0.530 |
DUS3L | MYADM | ENSP00000311977 | ENSP00000375649 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | Myeloid associated differentiation marker; Belongs to the MAL family | 0.585 |
DUS3L | RABEPK | ENSP00000311977 | ENSP00000362639 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport | 0.643 |
ERCC4 | C10orf55 | ENSP00000310520 | ENSP00000409225 | DNA repair endonuclease XPF; Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link; Belongs to the XPF family | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | 0.540 |
GRSF1 | C10orf55 | ENSP00000254799 | ENSP00000409225 | G-rich sequence factor 1; Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | 0.435 |
MYADM | C10orf55 | ENSP00000375649 | ENSP00000409225 | Myeloid associated differentiation marker; Belongs to the MAL family | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | 0.489 |
MYADM | DUS3L | ENSP00000375649 | ENSP00000311977 | Myeloid associated differentiation marker; Belongs to the MAL family | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | 0.585 |
MYADM | RABEPK | ENSP00000375649 | ENSP00000362639 | Myeloid associated differentiation marker; Belongs to the MAL family | Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport | 0.589 |
RABEPK | C10orf55 | ENSP00000362639 | ENSP00000409225 | Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | 0.556 |
RABEPK | DUS3L | ENSP00000362639 | ENSP00000311977 | Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | 0.643 |
RABEPK | MYADM | ENSP00000362639 | ENSP00000375649 | Rab9 effector protein with kelch motifs; Rab9 effector required for endosome to trans-Golgi network (TGN) transport | Myeloid associated differentiation marker; Belongs to the MAL family | 0.589 |