• Version:
  • 11.0 [archived version]
STRINGSTRING
BDH2 BDH2 MDGA1 MDGA1 ZG16B ZG16B ZBTB42 ZBTB42 PGBD1 PGBD1 FOXQ1 FOXQ1 ADSSL1 ADSSL1 OR52M1 OR52M1
"ZBTB42" - Zinc finger and BTB domain-containing protein 42 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
ZBTB42Zinc finger and BTB domain-containing protein 42; Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes; BTB domain containing (422 aa)    
Predicted Functional Partners:
PGBD1
PiggyBac transposable element-derived protein 1; Scavenger receptor cysteine rich domain containing; DNA transposon derived genes (809 aa)
           
  0.491
ZG16B
Zymogen granule protein 16B; Belongs to the jacalin lectin family (208 aa)
     
   
  0.491
ADSSL1
Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (500 aa)
           
  0.452
MDGA1
MAM domain-containing glycosylphosphatidylinositol anchor protein 1; Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2; I-set domain containing (955 aa)
           
  0.445
BDH2
3-hydroxybutyrate dehydrogenase type 2; Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity); Short chain dehydrogenase/reductase superfamily (245 aa)
       
 
  0.433
FOXQ1
Forkhead box protein Q1; Plays a role in hair follicle differentiation; Forkhead boxes (403 aa)
       
 
  0.412
OR52M1
Olfactory receptor 52M1; Odorant receptor; Olfactory receptors, family 52 (317 aa)
           
  0.410
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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