node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACOXL | ANAPC1 | ENSP00000407761 | ENSP00000339109 | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | Anaphase-promoting complex subunit 1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins- it mainly mediates the formation of ’Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains; Belongs to the APC1 family | 0.651 |
ACOXL | ANKRD23 | ENSP00000407761 | ENSP00000321679 | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | Ankyrin repeat domain-containing protein 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression; Ankyrin repeat domain containing | 0.614 |
ACOXL | ATP1B3 | ENSP00000407761 | ENSP00000286371 | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known; ATPase Na+/K+ transporting subunits | 0.566 |
ACOXL | FBLN7 | ENSP00000407761 | ENSP00000331411 | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | Fibulin-7; An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation; Fibulins | 0.531 |
ACOXL | HSD17B4 | ENSP00000407761 | ENSP00000420914 | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | Peroxisomal multifunctional enzyme type 2; Bifunctional enzyme acting on the peroxisomal beta- oxidation pathway for fatty acids. Catalyzes the formation of 3- ketoacyl-CoA intermediates from both straight-chain and 2-methyl- branched-chain fatty acids; Short chain dehydrogenase/reductase superfamily | 0.558 |
ACOXL | HTD2 | ENSP00000407761 | ENSP00000481593 | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | Hydroxyacyl-thioester dehydratase type 2, mitochondrial; Mitochondrial 3-hydroxyacyl-thioester dehydratase, which may be involved in fatty acid biosynthesis; Belongs to the HTD2 family | 0.558 |
ACOXL | LYG2 | ENSP00000407761 | ENSP00000327533 | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | Lysozyme g-like protein 2; May act as a potent antibacterial protein that may play a role in the innate immunity; Belongs to the glycosyl hydrolase 23 family | 0.664 |
ACOXL | PDCL3 | ENSP00000407761 | ENSP00000264254 | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | Phosducin-like protein 3; Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination; Belongs to the phosducin family | 0.638 |
ACOXL | SP140 | ENSP00000407761 | ENSP00000375899 | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | Nuclear body protein SP140; Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails; Bromodomain containing | 0.569 |
ACOXL | ZC3H6 | ENSP00000407761 | ENSP00000386764 | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | Zinc finger CCCH-type containing 6 | 0.625 |
ANAPC1 | ACOXL | ENSP00000339109 | ENSP00000407761 | Anaphase-promoting complex subunit 1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins- it mainly mediates the formation of ’Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains; Belongs to the APC1 family | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | 0.651 |
ANAPC1 | FBLN7 | ENSP00000339109 | ENSP00000331411 | Anaphase-promoting complex subunit 1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins- it mainly mediates the formation of ’Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains; Belongs to the APC1 family | Fibulin-7; An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation; Fibulins | 0.571 |
ANAPC1 | ZC3H6 | ENSP00000339109 | ENSP00000386764 | Anaphase-promoting complex subunit 1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins- it mainly mediates the formation of ’Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains; Belongs to the APC1 family | Zinc finger CCCH-type containing 6 | 0.632 |
ANKRD23 | ACOXL | ENSP00000321679 | ENSP00000407761 | Ankyrin repeat domain-containing protein 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression; Ankyrin repeat domain containing | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | 0.614 |
ANKRD23 | LYG2 | ENSP00000321679 | ENSP00000327533 | Ankyrin repeat domain-containing protein 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression; Ankyrin repeat domain containing | Lysozyme g-like protein 2; May act as a potent antibacterial protein that may play a role in the innate immunity; Belongs to the glycosyl hydrolase 23 family | 0.627 |
ANKRD23 | PDCL3 | ENSP00000321679 | ENSP00000264254 | Ankyrin repeat domain-containing protein 23; May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression; Ankyrin repeat domain containing | Phosducin-like protein 3; Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination; Belongs to the phosducin family | 0.604 |
ATP1B3 | ACOXL | ENSP00000286371 | ENSP00000407761 | Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known; ATPase Na+/K+ transporting subunits | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | 0.566 |
FBLN7 | ACOXL | ENSP00000331411 | ENSP00000407761 | Fibulin-7; An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation; Fibulins | Acyl-coenzyme A oxidase-like protein; acyl-CoA oxidase like; Belongs to the acyl-CoA oxidase family | 0.531 |
FBLN7 | ANAPC1 | ENSP00000331411 | ENSP00000339109 | Fibulin-7; An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation; Fibulins | Anaphase-promoting complex subunit 1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins- it mainly mediates the formation of ’Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains; Belongs to the APC1 family | 0.571 |
FBLN7 | ZC3H6 | ENSP00000331411 | ENSP00000386764 | Fibulin-7; An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation; Fibulins | Zinc finger CCCH-type containing 6 | 0.544 |