node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAM151B | GOLGA7 | ENSP00000282226 | ENSP00000350378 | Protein FAM151B; Family with sequence similarity 151 member B | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | 0.577 |
FAM151B | MEF2BNB | ENSP00000282226 | ENSP00000425864 | Protein FAM151B; Family with sequence similarity 151 member B | BLOC-1-related complex subunit 8; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor | 0.590 |
FAM151B | SLC25A44 | ENSP00000282226 | ENSP00000407560 | Protein FAM151B; Family with sequence similarity 151 member B | Solute carrier family 25 member 44 | 0.577 |
GOLGA7 | FAM151B | ENSP00000350378 | ENSP00000282226 | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | Protein FAM151B; Family with sequence similarity 151 member B | 0.577 |
GOLGA7 | MEF2BNB | ENSP00000350378 | ENSP00000425864 | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | BLOC-1-related complex subunit 8; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor | 0.549 |
GOLGA7 | SLC25A44 | ENSP00000350378 | ENSP00000407560 | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | Solute carrier family 25 member 44 | 0.556 |
IMPDH2 | SLC25A44 | ENSP00000321584 | ENSP00000407560 | Inosine-5’-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors | Solute carrier family 25 member 44 | 0.847 |
KCNK17 | SLC25A44 | ENSP00000362328 | ENSP00000407560 | Potassium channel subfamily K member 17; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Solute carrier family 25 member 44 | 0.609 |
MEF2BNB | FAM151B | ENSP00000425864 | ENSP00000282226 | BLOC-1-related complex subunit 8; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor | Protein FAM151B; Family with sequence similarity 151 member B | 0.590 |
MEF2BNB | GOLGA7 | ENSP00000425864 | ENSP00000350378 | BLOC-1-related complex subunit 8; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | 0.549 |
MEF2BNB | SLC25A44 | ENSP00000425864 | ENSP00000407560 | BLOC-1-related complex subunit 8; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor | Solute carrier family 25 member 44 | 0.566 |
MRPL47 | SLC25A44 | ENSP00000417602 | ENSP00000407560 | Mitochondrial ribosomal protein L47 | Solute carrier family 25 member 44 | 0.660 |
PMF1-BGLAP | PMF1 | ENSP00000357259 | ENSP00000357256 | Polyamine-modulated factor 1; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT | Polyamine-modulated factor 1; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT | 0.902 |
PMF1-BGLAP | SLC25A44 | ENSP00000357259 | ENSP00000407560 | Polyamine-modulated factor 1; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT | Solute carrier family 25 member 44 | 0.630 |
PMF1 | PMF1-BGLAP | ENSP00000357256 | ENSP00000357259 | Polyamine-modulated factor 1; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT | Polyamine-modulated factor 1; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT | 0.902 |
PMF1 | SLC25A44 | ENSP00000357256 | ENSP00000407560 | Polyamine-modulated factor 1; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT | Solute carrier family 25 member 44 | 0.745 |
SLC25A35 | SLC25A44 | ENSP00000369407 | ENSP00000407560 | Solute carrier family 25 member 35; Belongs to the mitochondrial carrier (TC 2.A.29) family | Solute carrier family 25 member 44 | 0.664 |
SLC25A44 | FAM151B | ENSP00000407560 | ENSP00000282226 | Solute carrier family 25 member 44 | Protein FAM151B; Family with sequence similarity 151 member B | 0.577 |
SLC25A44 | GOLGA7 | ENSP00000407560 | ENSP00000350378 | Solute carrier family 25 member 44 | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS | 0.556 |
SLC25A44 | IMPDH2 | ENSP00000407560 | ENSP00000321584 | Solute carrier family 25 member 44 | Inosine-5’-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors | 0.847 |