node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GALNT14 | MUC1 | ENSP00000314500 | ENSP00000484824 | Polypeptide N-acetylgalactosaminyltransferase 14 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | 0.948 |
GALNT14 | MUC12 | ENSP00000314500 | ENSP00000441929 | Polypeptide N-acetylgalactosaminyltransferase 14 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium; Mucins | 0.917 |
GALNT14 | MUC15 | ENSP00000314500 | ENSP00000416753 | Polypeptide N-acetylgalactosaminyltransferase 14 | Mucin-15; May play a role in the cell adhesion to the extracellular matrix; Mucins | 0.908 |
GALNT14 | MUC16 | ENSP00000314500 | ENSP00000381008 | Polypeptide N-acetylgalactosaminyltransferase 14 | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces; Mucins | 0.914 |
GALNT14 | MUC17 | ENSP00000314500 | ENSP00000302716 | Polypeptide N-acetylgalactosaminyltransferase 14 | Mucin-17; Probably plays a role in maintaining homeostasis on mucosal surfaces; Mucins | 0.910 |
GALNT14 | MUC4 | ENSP00000314500 | ENSP00000417498 | Polypeptide N-acetylgalactosaminyltransferase 14 | Mucin-4; May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. The MUC4-ERBB2 complex causes site-specific phosphorylation of the ERBB2 ’Tyr-1248’. In [...] | 0.921 |
GALNT14 | MUC5AC | ENSP00000314500 | ENSP00000485659 | Polypeptide N-acetylgalactosaminyltransferase 14 | Mucin-5AC; Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system; Mucins | 0.972 |
GALNT14 | MUC5B | ENSP00000314500 | ENSP00000436812 | Polypeptide N-acetylgalactosaminyltransferase 14 | Mucin-5B; Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus; Mucins | 0.914 |
GALNT14 | MUC6 | ENSP00000314500 | ENSP00000406861 | Polypeptide N-acetylgalactosaminyltransferase 14 | Mucin-6; May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis; Mucins | 0.922 |
GALNT14 | MUC7 | ENSP00000314500 | ENSP00000407422 | Polypeptide N-acetylgalactosaminyltransferase 14 | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili; Mucins | 0.977 |
MUC1 | GALNT14 | ENSP00000484824 | ENSP00000314500 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | Polypeptide N-acetylgalactosaminyltransferase 14 | 0.948 |
MUC1 | MUC12 | ENSP00000484824 | ENSP00000441929 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF- beta in intestinal epithelium; Mucins | 0.969 |
MUC1 | MUC15 | ENSP00000484824 | ENSP00000416753 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | Mucin-15; May play a role in the cell adhesion to the extracellular matrix; Mucins | 0.969 |
MUC1 | MUC16 | ENSP00000484824 | ENSP00000381008 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces; Mucins | 0.979 |
MUC1 | MUC17 | ENSP00000484824 | ENSP00000302716 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | Mucin-17; Probably plays a role in maintaining homeostasis on mucosal surfaces; Mucins | 0.966 |
MUC1 | MUC4 | ENSP00000484824 | ENSP00000417498 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | Mucin-4; May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. The MUC4-ERBB2 complex causes site-specific phosphorylation of the ERBB2 ’Tyr-1248’. In [...] | 0.986 |
MUC1 | MUC5AC | ENSP00000484824 | ENSP00000485659 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | Mucin-5AC; Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system; Mucins | 0.989 |
MUC1 | MUC5B | ENSP00000484824 | ENSP00000436812 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | Mucin-5B; Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus; Mucins | 0.980 |
MUC1 | MUC6 | ENSP00000484824 | ENSP00000406861 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | Mucin-6; May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis; Mucins | 0.985 |
MUC1 | MUC7 | ENSP00000484824 | ENSP00000407422 | Mucin-1; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack; CD molecules | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili; Mucins | 0.972 |