ACBD4 protein (human) - STRING database

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ACBD4

acyl-CoA binding domain containing 4 (341 aa)

Predicted Functional Partners:

VAPB

0.623

FAM219B

0.532

DCAKD

0.473

FAM109A

0.448

RUSC1

0.446

C10orf32

0.443

PPP1R3F

0.420

MYO7B

0.413

CREBL2

0.403

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACBD4	C10orf32	ENSP00000405969	ENSP00000342331	acyl-CoA binding domain containing 4	BLOC-1-related complex subunit 7; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS7 family	0.443
ACBD4	CREBL2	ENSP00000405969	ENSP00000228865	acyl-CoA binding domain containing 4	cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily	0.403
ACBD4	DCAKD	ENSP00000405969	ENSP00000308515	acyl-CoA binding domain containing 4	dephospho-CoA kinase domain containing	0.473
ACBD4	FAM109A	ENSP00000405969	ENSP00000354461	acyl-CoA binding domain containing 4	Sesquipedalian-1; Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane; Pleckstrin homology domain containing	0.448
ACBD4	FAM219B	ENSP00000405969	ENSP00000350260	acyl-CoA binding domain containing 4	Protein FAM219B; Family with sequence similarity 219 member B	0.532
ACBD4	MYO7B	ENSP00000405969	ENSP00000415090	acyl-CoA binding domain containing 4	Unconventional myosin-VIIb; Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. May link the complex to the actin core bundle of microvilli (Probable); FERM domain containing	0.413
ACBD4	PPP1R3F	ENSP00000405969	ENSP00000055335	acyl-CoA binding domain containing 4	Protein phosphatase 1 regulatory subunit 3F; Glycogen-targeting subunit for protein phosphatase 1 (PP1)	0.420
ACBD4	RUSC1	ENSP00000405969	ENSP00000357336	acyl-CoA binding domain containing 4	RUN and SH3 domain-containing protein 1; Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway	0.446
ACBD4	VAPB	ENSP00000405969	ENSP00000417175	acyl-CoA binding domain containing 4	Vesicle-associated membrane protein-associated protein B/C; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation	0.623
C10orf32	ACBD4	ENSP00000342331	ENSP00000405969	BLOC-1-related complex subunit 7; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS7 family	acyl-CoA binding domain containing 4	0.443
C10orf32	FAM109A	ENSP00000342331	ENSP00000354461	BLOC-1-related complex subunit 7; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS7 family	Sesquipedalian-1; Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane; Pleckstrin homology domain containing	0.414
C10orf32	FAM219B	ENSP00000342331	ENSP00000350260	BLOC-1-related complex subunit 7; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS7 family	Protein FAM219B; Family with sequence similarity 219 member B	0.476
CREBL2	ACBD4	ENSP00000228865	ENSP00000405969	cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily	acyl-CoA binding domain containing 4	0.403
DCAKD	ACBD4	ENSP00000308515	ENSP00000405969	dephospho-CoA kinase domain containing	acyl-CoA binding domain containing 4	0.473
FAM109A	ACBD4	ENSP00000354461	ENSP00000405969	Sesquipedalian-1; Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane; Pleckstrin homology domain containing	acyl-CoA binding domain containing 4	0.448
FAM109A	C10orf32	ENSP00000354461	ENSP00000342331	Sesquipedalian-1; Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane; Pleckstrin homology domain containing	BLOC-1-related complex subunit 7; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS7 family	0.414
FAM109A	FAM219B	ENSP00000354461	ENSP00000350260	Sesquipedalian-1; Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane; Pleckstrin homology domain containing	Protein FAM219B; Family with sequence similarity 219 member B	0.491
FAM219B	ACBD4	ENSP00000350260	ENSP00000405969	Protein FAM219B; Family with sequence similarity 219 member B	acyl-CoA binding domain containing 4	0.532
FAM219B	C10orf32	ENSP00000350260	ENSP00000342331	Protein FAM219B; Family with sequence similarity 219 member B	BLOC-1-related complex subunit 7; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS7 family	0.476
FAM219B	FAM109A	ENSP00000350260	ENSP00000354461	Protein FAM219B; Family with sequence similarity 219 member B	Sesquipedalian-1; Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane; Pleckstrin homology domain containing	0.491

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