node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CNTD2 | SVOPL | ENSP00000396755 | ENSP00000405482 | Cyclin N-terminal domain containing 2 | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily | 0.730 |
CNTD2 | ZNF205 | ENSP00000396755 | ENSP00000480401 | Cyclin N-terminal domain containing 2 | Zinc finger protein 205; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.779 |
LRGUK | NDUFA9 | ENSP00000285928 | ENSP00000266544 | Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis; Cilia and flagella associated | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH-ubiquinone oxidoreductase supernumerary subunits | 0.475 |
LRGUK | SVOPL | ENSP00000285928 | ENSP00000405482 | Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis; Cilia and flagella associated | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily | 0.761 |
MFSD10 | MFSD11 | ENSP00000332646 | ENSP00000464932 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | 0.770 |
MFSD10 | MFSD2A | ENSP00000332646 | ENSP00000361895 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...] | 0.623 |
MFSD10 | MFSD5 | ENSP00000332646 | ENSP00000442688 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily | 0.801 |
MFSD10 | MFSD8 | ENSP00000332646 | ENSP00000296468 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily | 0.737 |
MFSD10 | SVOPL | ENSP00000332646 | ENSP00000405482 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily | 0.766 |
MFSD10 | UNC93A | ENSP00000332646 | ENSP00000230256 | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | Unc-93 homolog A; Belongs to the unc-93 family | 0.609 |
MFSD11 | MFSD10 | ENSP00000464932 | ENSP00000332646 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | 0.770 |
MFSD11 | MFSD2A | ENSP00000464932 | ENSP00000361895 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...] | 0.676 |
MFSD11 | MFSD5 | ENSP00000464932 | ENSP00000442688 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily | 0.873 |
MFSD11 | MFSD8 | ENSP00000464932 | ENSP00000296468 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily | 0.755 |
MFSD11 | SVOPL | ENSP00000464932 | ENSP00000405482 | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily | 0.816 |
MFSD2A | MFSD10 | ENSP00000361895 | ENSP00000332646 | Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...] | Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump | 0.623 |
MFSD2A | MFSD11 | ENSP00000361895 | ENSP00000464932 | Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...] | UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family | 0.676 |
MFSD2A | MFSD5 | ENSP00000361895 | ENSP00000442688 | Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...] | Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily | 0.603 |
MFSD2A | MFSD8 | ENSP00000361895 | ENSP00000296468 | Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...] | Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily | 0.581 |
MFSD2A | SVOPL | ENSP00000361895 | ENSP00000405482 | Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...] | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily | 0.668 |