SVOPL protein (human) - STRING database

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Score

SVOPL

Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily (492 aa)

Predicted Functional Partners:

MFSD11

0.816

MFSD5

0.801

MFSD10

0.766

LRGUK

0.761

UNC93A

0.746

CNTD2

0.730

ZNF205

0.725

MFSD8

0.712

NDUFA9

0.708

MFSD2A

0.668

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTD2	SVOPL	ENSP00000396755	ENSP00000405482	Cyclin N-terminal domain containing 2	Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily	0.730
CNTD2	ZNF205	ENSP00000396755	ENSP00000480401	Cyclin N-terminal domain containing 2	Zinc finger protein 205; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.779
LRGUK	NDUFA9	ENSP00000285928	ENSP00000266544	Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis; Cilia and flagella associated	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH-ubiquinone oxidoreductase supernumerary subunits	0.475
LRGUK	SVOPL	ENSP00000285928	ENSP00000405482	Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis; Cilia and flagella associated	Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily	0.761
MFSD10	MFSD11	ENSP00000332646	ENSP00000464932	Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump	UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family	0.770
MFSD10	MFSD2A	ENSP00000332646	ENSP00000361895	Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump	Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...]	0.623
MFSD10	MFSD5	ENSP00000332646	ENSP00000442688	Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump	Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily	0.801
MFSD10	MFSD8	ENSP00000332646	ENSP00000296468	Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump	Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily	0.737
MFSD10	SVOPL	ENSP00000332646	ENSP00000405482	Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump	Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily	0.766
MFSD10	UNC93A	ENSP00000332646	ENSP00000230256	Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump	Unc-93 homolog A; Belongs to the unc-93 family	0.609
MFSD11	MFSD10	ENSP00000464932	ENSP00000332646	UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family	Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump	0.770
MFSD11	MFSD2A	ENSP00000464932	ENSP00000361895	UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family	Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...]	0.676
MFSD11	MFSD5	ENSP00000464932	ENSP00000442688	UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family	Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily	0.873
MFSD11	MFSD8	ENSP00000464932	ENSP00000296468	UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family	Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily	0.755
MFSD11	SVOPL	ENSP00000464932	ENSP00000405482	UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family	Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily	0.816
MFSD2A	MFSD10	ENSP00000361895	ENSP00000332646	Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...]	Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump	0.623
MFSD2A	MFSD11	ENSP00000361895	ENSP00000464932	Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...]	UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family	0.676
MFSD2A	MFSD5	ENSP00000361895	ENSP00000442688	Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...]	Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily	0.603
MFSD2A	MFSD8	ENSP00000361895	ENSP00000296468	Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...]	Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily	0.581
MFSD2A	SVOPL	ENSP00000361895	ENSP00000405482	Sodium-dependent lysophosphatidylcholine symporter 1; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity). Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fa [...]	Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily	0.668

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