| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BLK | NKAPL | ENSP00000259089 | ENSP00000345716 | Tyrosine-protein kinase Blk; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis d [...] | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis | 0.405 |
| BLK | ZSCAN9 | ENSP00000259089 | ENSP00000404074 | Tyrosine-protein kinase Blk; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis d [...] | Zinc finger and SCAN domain containing 9 | 0.429 |
| GPR20 | ZSCAN9 | ENSP00000366970 | ENSP00000404074 | G-protein coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP; G protein-coupled receptors, Class A orphans | Zinc finger and SCAN domain containing 9 | 0.473 |
| MTG1 | ZSCAN9 | ENSP00000323047 | ENSP00000404074 | Mitochondrial ribosome-associated GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily | Zinc finger and SCAN domain containing 9 | 0.428 |
| NKAP | PRKCQ | ENSP00000360464 | ENSP00000263125 | NF-kappa-B-activating protein; Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter; Belongs to the NKAP family | Protein kinase C theta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that mediates non- redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple transcription factors such as NF-kappa-B, JUN, NFATC1 and NFATC2. In TCR-CD3/CD28-co-stimulated T-cells, is required for the activation of NF-kappa-B and JUN, which in turn are essential for IL2 production, and participates in the calcium-dependent NFATC1 and NFATC2 transact [...] | 0.439 |
| NKAP | ZSCAN9 | ENSP00000360464 | ENSP00000404074 | NF-kappa-B-activating protein; Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter; Belongs to the NKAP family | Zinc finger and SCAN domain containing 9 | 0.517 |
| NKAPL | BLK | ENSP00000345716 | ENSP00000259089 | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis | Tyrosine-protein kinase Blk; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis d [...] | 0.405 |
| NKAPL | PRKCQ | ENSP00000345716 | ENSP00000263125 | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis | Protein kinase C theta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that mediates non- redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple transcription factors such as NF-kappa-B, JUN, NFATC1 and NFATC2. In TCR-CD3/CD28-co-stimulated T-cells, is required for the activation of NF-kappa-B and JUN, which in turn are essential for IL2 production, and participates in the calcium-dependent NFATC1 and NFATC2 transact [...] | 0.511 |
| NKAPL | ZSCAN9 | ENSP00000345716 | ENSP00000404074 | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis | Zinc finger and SCAN domain containing 9 | 0.651 |
| PRKCQ | NKAP | ENSP00000263125 | ENSP00000360464 | Protein kinase C theta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that mediates non- redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple transcription factors such as NF-kappa-B, JUN, NFATC1 and NFATC2. In TCR-CD3/CD28-co-stimulated T-cells, is required for the activation of NF-kappa-B and JUN, which in turn are essential for IL2 production, and participates in the calcium-dependent NFATC1 and NFATC2 transact [...] | NF-kappa-B-activating protein; Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter; Belongs to the NKAP family | 0.439 |
| PRKCQ | NKAPL | ENSP00000263125 | ENSP00000345716 | Protein kinase C theta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that mediates non- redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple transcription factors such as NF-kappa-B, JUN, NFATC1 and NFATC2. In TCR-CD3/CD28-co-stimulated T-cells, is required for the activation of NF-kappa-B and JUN, which in turn are essential for IL2 production, and participates in the calcium-dependent NFATC1 and NFATC2 transact [...] | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis | 0.511 |
| PRKCQ | ZSCAN9 | ENSP00000263125 | ENSP00000404074 | Protein kinase C theta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that mediates non- redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple transcription factors such as NF-kappa-B, JUN, NFATC1 and NFATC2. In TCR-CD3/CD28-co-stimulated T-cells, is required for the activation of NF-kappa-B and JUN, which in turn are essential for IL2 production, and participates in the calcium-dependent NFATC1 and NFATC2 transact [...] | Zinc finger and SCAN domain containing 9 | 0.530 |
| TFF3 | ZSCAN9 | ENSP00000430690 | ENSP00000404074 | Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) | Zinc finger and SCAN domain containing 9 | 0.461 |
| TM2D1 | ZSCAN9 | ENSP00000475700 | ENSP00000404074 | TM2 domain-containing protein 1; May participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42 | Zinc finger and SCAN domain containing 9 | 0.447 |
| ZNF24 | ZSCAN23 | ENSP00000261332 | ENSP00000289788 | Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5’-TCAT-3’ DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family | Zinc finger and SCAN domain-containing protein 23; May be involved in transcriptional regulation; SCAN domain containing | 0.527 |
| ZNF24 | ZSCAN9 | ENSP00000261332 | ENSP00000404074 | Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5’-TCAT-3’ DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family | Zinc finger and SCAN domain containing 9 | 0.543 |
| ZSCAN23 | ZNF24 | ENSP00000289788 | ENSP00000261332 | Zinc finger and SCAN domain-containing protein 23; May be involved in transcriptional regulation; SCAN domain containing | Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5’-TCAT-3’ DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.527 |
| ZSCAN23 | ZSCAN9 | ENSP00000289788 | ENSP00000404074 | Zinc finger and SCAN domain-containing protein 23; May be involved in transcriptional regulation; SCAN domain containing | Zinc finger and SCAN domain containing 9 | 0.500 |
| ZSCAN9 | BLK | ENSP00000404074 | ENSP00000259089 | Zinc finger and SCAN domain containing 9 | Tyrosine-protein kinase Blk; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis d [...] | 0.429 |
| ZSCAN9 | GPR20 | ENSP00000404074 | ENSP00000366970 | Zinc finger and SCAN domain containing 9 | G-protein coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP; G protein-coupled receptors, Class A orphans | 0.473 |
