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  • 11.0 [archived version]
STRINGSTRING
SCG2 SCG2 CHGB CHGB CSH1 CSH1 SCG3 SCG3 CSH2 CSH2 CGB8 CGB8 CGA CGA CGB CGB CHGA CHGA CGB5 CGB5 NGB NGB
"CGB8" - Choriogonadotropin subunit beta variant 2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CGB8Choriogonadotropin subunit beta variant 2; Chorionic gonadotropin beta subunit 8; Belongs to the glycoprotein hormones subunit beta family (165 aa)    
Predicted Functional Partners:
CGB5
Chorionic gonadotropin beta subunit 5 (165 aa)
      
 
0.837
CHGB
Secretogranin-1; Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides (677 aa)
            
  0.830
CGB
Chorionic gonadotropin, beta polypeptide; Belongs to the glycoprotein hormones subunit beta family (165 aa)
        
 
0.801
SCG2
Secretogranin-2; Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides; Granins (617 aa)
      
   
  0.737
CHGA
Chromogranin-A; Pancreastatin- Strongly inhibits glucose induced insulin release from the pancreas; Belongs to the chromogranin/secretogranin protein family (457 aa)
      
   
  0.678
SCG3
Secretogranin-3; Secretogranin III; Granins (468 aa)
            
  0.669
CSH2
Chorionic somatomammotropin hormone 2; Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization; Growth hormone family (217 aa)
      
   
  0.662
CGA
Glycoprotein hormones, alpha polypeptide; Belongs to the glycoprotein hormones subunit alpha family (147 aa)
      
   
  0.595
CSH1
Chorionic somatomammotropin hormone 1; Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization; Belongs to the somatotropin/prolactin family (217 aa)
      
   
  0.573
NGB
Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis (151 aa)
      
   
  0.552
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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