| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BHMG1 | CYS1 | ENSP00000402674 | ENSP00000371234 | Basic helix-loop-helix and HMG box domain-containing protein 1 | Cystin-1; Cystin 1 | 0.473 |
| BHMG1 | DMPK | ENSP00000402674 | ENSP00000345997 | Basic helix-loop-helix and HMG box domain-containing protein 1 | Myotonin-protein kinase; Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeo [...] | 0.400 |
| BHMG1 | DMWD | ENSP00000402674 | ENSP00000270223 | Basic helix-loop-helix and HMG box domain-containing protein 1 | Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing | 0.564 |
| BHMG1 | FBXO46 | ENSP00000402674 | ENSP00000410007 | Basic helix-loop-helix and HMG box domain-containing protein 1 | F-box only protein 46; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | 0.670 |
| BHMG1 | QPCTL | ENSP00000402674 | ENSP00000012049 | Basic helix-loop-helix and HMG box domain-containing protein 1 | Glutaminyl-peptide cyclotransferase-like protein; Responsible for the biosynthesis of pyroglutamyl peptides | 0.540 |
| BHMG1 | RSPH6A | ENSP00000402674 | ENSP00000221538 | Basic helix-loop-helix and HMG box domain-containing protein 1 | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | 0.571 |
| BHMG1 | SIX5 | ENSP00000402674 | ENSP00000316842 | Basic helix-loop-helix and HMG box domain-containing protein 1 | Homeobox protein SIX5; Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5’-GGTGTCAG-3’ motif present in the ARE regulatory element of ATP1A1. Binds a 5’- TCA[AG][AG]TTNC-3’ motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity); SINE class homeoboxes | 0.491 |
| CYS1 | BHMG1 | ENSP00000371234 | ENSP00000402674 | Cystin-1; Cystin 1 | Basic helix-loop-helix and HMG box domain-containing protein 1 | 0.473 |
| DMPK | BHMG1 | ENSP00000345997 | ENSP00000402674 | Myotonin-protein kinase; Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeo [...] | Basic helix-loop-helix and HMG box domain-containing protein 1 | 0.400 |
| DMPK | DMWD | ENSP00000345997 | ENSP00000270223 | Myotonin-protein kinase; Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeo [...] | Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing | 0.638 |
| DMPK | SIX5 | ENSP00000345997 | ENSP00000316842 | Myotonin-protein kinase; Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeo [...] | Homeobox protein SIX5; Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5’-GGTGTCAG-3’ motif present in the ARE regulatory element of ATP1A1. Binds a 5’- TCA[AG][AG]TTNC-3’ motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity); SINE class homeoboxes | 0.714 |
| DMWD | BHMG1 | ENSP00000270223 | ENSP00000402674 | Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing | Basic helix-loop-helix and HMG box domain-containing protein 1 | 0.564 |
| DMWD | DMPK | ENSP00000270223 | ENSP00000345997 | Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing | Myotonin-protein kinase; Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeo [...] | 0.638 |
| DMWD | RSPH6A | ENSP00000270223 | ENSP00000221538 | Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | 0.813 |
| DMWD | SIX5 | ENSP00000270223 | ENSP00000316842 | Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing | Homeobox protein SIX5; Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5’-GGTGTCAG-3’ motif present in the ARE regulatory element of ATP1A1. Binds a 5’- TCA[AG][AG]TTNC-3’ motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 (By similarity); SINE class homeoboxes | 0.619 |
| FBXO46 | BHMG1 | ENSP00000410007 | ENSP00000402674 | F-box only protein 46; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | Basic helix-loop-helix and HMG box domain-containing protein 1 | 0.670 |
| FBXO46 | RSPH6A | ENSP00000410007 | ENSP00000221538 | F-box only protein 46; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | 0.421 |
| QPCTL | BHMG1 | ENSP00000012049 | ENSP00000402674 | Glutaminyl-peptide cyclotransferase-like protein; Responsible for the biosynthesis of pyroglutamyl peptides | Basic helix-loop-helix and HMG box domain-containing protein 1 | 0.540 |
| RSPH6A | BHMG1 | ENSP00000221538 | ENSP00000402674 | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | Basic helix-loop-helix and HMG box domain-containing protein 1 | 0.571 |
| RSPH6A | DMWD | ENSP00000221538 | ENSP00000270223 | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing | 0.813 |
