• Version:
  • 11.0 [archived version]
STRINGSTRING
CDRT15L2 CDRT15L2 MAP4K5 MAP4K5 NUDT8 NUDT8 ZNF18 ZNF18 CDRT15 CDRT15 SHISA6 SHISA6 TEKT3 TEKT3 TVP23B TVP23B CDRT1 CDRT1 HS3ST3A1 HS3ST3A1 HS3ST3B1 HS3ST3B1
"CDRT15" - CMT1A duplicated region transcript 15 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
CDRT15CMT1A duplicated region transcript 15 (188 aa)    
Predicted Functional Partners:
CDRT15L2
CMT1A duplicated region transcript 15 like 2 (281 aa)
     
   
0.700
CDRT1
CMT1A duplicated region transcript 1 protein; F-box and WD repeat domain containing (752 aa)
           
  0.679
TVP23B
Trans-golgi network vesicle protein 23 homolog B; Belongs to the TVP23 family (205 aa)
           
  0.670
ZNF18
Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (549 aa)
           
  0.634
HS3ST3B1
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anti [...] (390 aa)
           
  0.629
SHISA6
Protein shisa-6 homolog; Shisa family member 6 (551 aa)
           
  0.560
TEKT3
Tektin-3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity); Tektins (490 aa)
           
  0.528
HS3ST3A1
Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anti [...] (406 aa)
           
  0.514
NUDT8
Nucleoside diphosphate-linked moiety X motif 8; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Nudix hydrolase family (236 aa)
       
      0.513
MAP4K5
Mitogen-activated protein kinase kinase kinase kinase 5; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway; Mitogen-activated protein kinase kinase kinase kinases (846 aa)
       
      0.513
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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