PRSS48 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PRSS48

Serine protease 48; Belongs to the peptidase S1 family (328 aa)

Predicted Functional Partners:

OR11G2

0.640

WFDC3

0.558

AIM1L

0.542

MARCH10

0.539

CCT6B

0.530

PCDHB16

0.518

SHROOM1

0.515

DCP1B

0.492

RHBDL2

0.482

CPAMD8

0.481

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIM1L	MARCH10	ENSP00000310435	ENSP00000463080	Beta/gamma crystallin domain-containing protein 2; Absent in melanoma 1-like; Belongs to the beta/gamma-crystallin family	Probable E3 ubiquitin-protein ligase MARCH10; E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates; Membrane associated ring-CH-type fingers	0.414
AIM1L	OR11G2	ENSP00000310435	ENSP00000349930	Beta/gamma crystallin domain-containing protein 2; Absent in melanoma 1-like; Belongs to the beta/gamma-crystallin family	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	0.477
AIM1L	PCDHB16	ENSP00000310435	ENSP00000477314	Beta/gamma crystallin domain-containing protein 2; Absent in melanoma 1-like; Belongs to the beta/gamma-crystallin family	Protocadherin beta-16; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	0.401
AIM1L	PRSS48	ENSP00000310435	ENSP00000401328	Beta/gamma crystallin domain-containing protein 2; Absent in melanoma 1-like; Belongs to the beta/gamma-crystallin family	Serine protease 48; Belongs to the peptidase S1 family	0.542
AIM1L	WFDC3	ENSP00000310435	ENSP00000243938	Beta/gamma crystallin domain-containing protein 2; Absent in melanoma 1-like; Belongs to the beta/gamma-crystallin family	WAP four-disulfide core domain containing	0.430
CCT6B	OR11G2	ENSP00000327191	ENSP00000349930	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	0.455
CCT6B	PRSS48	ENSP00000327191	ENSP00000401328	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	Serine protease 48; Belongs to the peptidase S1 family	0.530
CCT6B	WFDC3	ENSP00000327191	ENSP00000243938	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	WAP four-disulfide core domain containing	0.420
CPAMD8	OR11G2	ENSP00000402505	ENSP00000349930	C3 and PZP like, alpha-2-macroglobulin domain containing 8; Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	0.441
CPAMD8	PRSS48	ENSP00000402505	ENSP00000401328	C3 and PZP like, alpha-2-macroglobulin domain containing 8; Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family	Serine protease 48; Belongs to the peptidase S1 family	0.481
DCP1B	OR11G2	ENSP00000280665	ENSP00000349930	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5’-phosphorylated mRNA fragment and 7m-GDP (By similarity)	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	0.441
DCP1B	PRSS48	ENSP00000280665	ENSP00000401328	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5’-phosphorylated mRNA fragment and 7m-GDP (By similarity)	Serine protease 48; Belongs to the peptidase S1 family	0.492
MARCH10	AIM1L	ENSP00000463080	ENSP00000310435	Probable E3 ubiquitin-protein ligase MARCH10; E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates; Membrane associated ring-CH-type fingers	Beta/gamma crystallin domain-containing protein 2; Absent in melanoma 1-like; Belongs to the beta/gamma-crystallin family	0.414
MARCH10	OR11G2	ENSP00000463080	ENSP00000349930	Probable E3 ubiquitin-protein ligase MARCH10; E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates; Membrane associated ring-CH-type fingers	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	0.489
MARCH10	PCDHB16	ENSP00000463080	ENSP00000477314	Probable E3 ubiquitin-protein ligase MARCH10; E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates; Membrane associated ring-CH-type fingers	Protocadherin beta-16; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	0.400
MARCH10	PRSS48	ENSP00000463080	ENSP00000401328	Probable E3 ubiquitin-protein ligase MARCH10; E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates; Membrane associated ring-CH-type fingers	Serine protease 48; Belongs to the peptidase S1 family	0.539
MARCH10	WFDC3	ENSP00000463080	ENSP00000243938	Probable E3 ubiquitin-protein ligase MARCH10; E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates; Membrane associated ring-CH-type fingers	WAP four-disulfide core domain containing	0.444
OR11G2	AIM1L	ENSP00000349930	ENSP00000310435	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	Beta/gamma crystallin domain-containing protein 2; Absent in melanoma 1-like; Belongs to the beta/gamma-crystallin family	0.477
OR11G2	CCT6B	ENSP00000349930	ENSP00000327191	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	0.455
OR11G2	CPAMD8	ENSP00000349930	ENSP00000402505	Olfactory receptor 11G2; Odorant receptor; Olfactory receptors, family 11	C3 and PZP like, alpha-2-macroglobulin domain containing 8; Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family	0.441

page 1 of 3

Network

Cooccurrence

Experiments

Neighborhood

Textmining

Fusion

Databases

Coexpression

© STRING Consortium 2020

Credits

Access

Info

About