SS18L2 protein (human) - STRING database

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SS18L2

SS18-like protein 2; SS18 like 2; Belongs to the SS18 family (77 aa)

Predicted Functional Partners:

CRAMP1L

0.840

SSX4B

0.745

SNRPG

0.738

SSX4

0.721

SSX1

0.649

SSX2

0.643

ZNF557

0.637

CCDC115

0.589

MRPL51

0.570

RPMS17

0.566

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC115	MRPL51	ENSP00000259229	ENSP00000229238	Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis	Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family	0.589
CCDC115	RPMS17	ENSP00000259229	ENSP00000285298	Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis	Mitochondrial ribosomal protein S17; Belongs to the universal ribosomal protein uS17 family	0.530
CCDC115	SS18L2	ENSP00000259229	ENSP00000401115	Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	0.589
CRAMP1L	SS18L2	ENSP00000380559	ENSP00000401115	Crm, cramped-like (Drosophila)	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	0.840
MRPL51	CCDC115	ENSP00000229238	ENSP00000259229	Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family	Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis	0.589
MRPL51	RPMS17	ENSP00000229238	ENSP00000285298	Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family	Mitochondrial ribosomal protein S17; Belongs to the universal ribosomal protein uS17 family	0.904
MRPL51	SS18L2	ENSP00000229238	ENSP00000401115	Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	0.570
RPMS17	CCDC115	ENSP00000285298	ENSP00000259229	Mitochondrial ribosomal protein S17; Belongs to the universal ribosomal protein uS17 family	Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis	0.530
RPMS17	MRPL51	ENSP00000285298	ENSP00000229238	Mitochondrial ribosomal protein S17; Belongs to the universal ribosomal protein uS17 family	Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family	0.904
RPMS17	SS18L2	ENSP00000285298	ENSP00000401115	Mitochondrial ribosomal protein S17; Belongs to the universal ribosomal protein uS17 family	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	0.566
SNRPG	SS18L2	ENSP00000272348	ENSP00000401115	Small nuclear ribonucleoprotein G; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	0.738
SS18L2	CCDC115	ENSP00000401115	ENSP00000259229	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis	0.589
SS18L2	CRAMP1L	ENSP00000401115	ENSP00000380559	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	Crm, cramped-like (Drosophila)	0.840
SS18L2	MRPL51	ENSP00000401115	ENSP00000229238	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family	0.570
SS18L2	RPMS17	ENSP00000401115	ENSP00000285298	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	Mitochondrial ribosomal protein S17; Belongs to the universal ribosomal protein uS17 family	0.566
SS18L2	SNRPG	ENSP00000401115	ENSP00000272348	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	Small nuclear ribonucleoprotein G; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing	0.738
SS18L2	SSX1	ENSP00000401115	ENSP00000366118	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	Protein SSX1; Could act as a modulator of transcription; Belongs to the SSX family	0.649
SS18L2	SSX2	ENSP00000401115	ENSP00000338796	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	Synovial sarcoma, X breakpoint 2; SSX family member 2	0.643
SS18L2	SSX4	ENSP00000401115	ENSP00000469011	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	Synovial sarcoma, X breakpoint 4; Could act as a modulator of transcription	0.721
SS18L2	SSX4B	ENSP00000401115	ENSP00000469394	SS18-like protein 2; SS18 like 2; Belongs to the SS18 family	Protein SSX4; Could act as a modulator of transcription	0.745

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