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STRINGSTRING
TRIOBP TRIOBP TACC2 TACC2 UBTF UBTF CEACAM21 CEACAM21 ZNF780A ZNF780A C19orf47 C19orf47 TTC9B TTC9B CNTD2 CNTD2 TIGD2 TIGD2 C19orf54 C19orf54 TMEM91 TMEM91
"ZNF780A" - Zinc finger protein 780A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF780AZinc finger protein 780A; May be involved in transcriptional regulation; Zinc fingers C2H2-type (642 aa)    
Predicted Functional Partners:
TACC2
Transforming acidic coiled-coil-containing protein 2; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker (2948 aa)
        
 
  0.634
TRIOBP
TRIO and F-actin-binding protein; May regulate actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin. The localized formation of TARA and TRIO complexes coordinates the amount of F-actin present in stress fibers. May also serve as a linker protein to recruit proteins required for F-actin formation and turnover; Deafness associated genes (2365 aa)
            
  0.623
C19orf47
Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 (422 aa)
            
  0.583
TIGD2
Tigger transposable element-derived protein 2; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes (525 aa)
        
 
  0.574
C19orf54
UPF0692 protein C19orf54; Chromosome 19 open reading frame 54; Belongs to the UPF0692 family (351 aa)
            
  0.570
TTC9B
Tetratricopeptide repeat domain containing (239 aa)
            
  0.545
TMEM91
Interferon induced transmembrane protein domain containing; Belongs to the CD225/Dispanin family (172 aa)
            
  0.543
UBTF
Nucleolar transcription factor 1; Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element (764 aa)
        
 
  0.524
CNTD2
Cyclin N-terminal domain containing 2 (307 aa)
        
 
  0.520
CEACAM21
Carcinoembryonic antigen related cell adhesion molecule family; Belongs to the immunoglobulin superfamily. CEA family (293 aa)
            
  0.518
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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