node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1orf159 | CCDC103 | ENSP00000400736 | ENSP00000391692 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | Coiled-coil domain containing 103; Dynein-attachment factor required for cilia motility; Belongs to the CCDC103/PR46b family | 0.422 |
C1orf159 | COMMD4 | ENSP00000400736 | ENSP00000267935 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | COMM domain-containing protein 4; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Down-regulates activation of NF-kappa-B | 0.499 |
C1orf159 | DENND4A | ENSP00000400736 | ENSP00000391167 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | C-myc promoter-binding protein; Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. According to PubMed-8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter; DENN/MADD domain containing | 0.445 |
C1orf159 | GSPT2 | ENSP00000400736 | ENSP00000341247 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons | 0.424 |
C1orf159 | OR10J3 | ENSP00000400736 | ENSP00000331789 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | Olfactory receptor 10J3; Odorant receptor; Olfactory receptors, family 10 | 0.530 |
C1orf159 | PLEKHS1 | ENSP00000400736 | ENSP00000358316 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | Pleckstrin homology domain containing S1 | 0.474 |
C1orf159 | PPP1R14C | ENSP00000400736 | ENSP00000355260 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | Protein phosphatase 1 regulatory subunit 14C; Inhibitor of the PP1 regulatory subunit PPP1CA | 0.400 |
C1orf159 | TMEM57 | ENSP00000400736 | ENSP00000363463 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | Macoilin; Transmembrane protein 57 | 0.442 |
C1orf159 | UXS1 | ENSP00000400736 | ENSP00000283148 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | UDP-glucuronic acid decarboxylase 1; Catalyzes the NAD-dependent decarboxylation of UDP- glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis; Short chain dehydrogenase/reductase superfamily | 0.446 |
CCDC103 | C1orf159 | ENSP00000391692 | ENSP00000400736 | Coiled-coil domain containing 103; Dynein-attachment factor required for cilia motility; Belongs to the CCDC103/PR46b family | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | 0.422 |
CCDC103 | OR10J3 | ENSP00000391692 | ENSP00000331789 | Coiled-coil domain containing 103; Dynein-attachment factor required for cilia motility; Belongs to the CCDC103/PR46b family | Olfactory receptor 10J3; Odorant receptor; Olfactory receptors, family 10 | 0.400 |
COMMD4 | C1orf159 | ENSP00000267935 | ENSP00000400736 | COMM domain-containing protein 4; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Down-regulates activation of NF-kappa-B | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | 0.499 |
COMMD4 | DENND4A | ENSP00000267935 | ENSP00000391167 | COMM domain-containing protein 4; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Down-regulates activation of NF-kappa-B | C-myc promoter-binding protein; Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. According to PubMed-8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter; DENN/MADD domain containing | 0.410 |
COMMD4 | OR10J3 | ENSP00000267935 | ENSP00000331789 | COMM domain-containing protein 4; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Down-regulates activation of NF-kappa-B | Olfactory receptor 10J3; Odorant receptor; Olfactory receptors, family 10 | 0.473 |
COMMD4 | TMEM57 | ENSP00000267935 | ENSP00000363463 | COMM domain-containing protein 4; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Down-regulates activation of NF-kappa-B | Macoilin; Transmembrane protein 57 | 0.416 |
DENND4A | C1orf159 | ENSP00000391167 | ENSP00000400736 | C-myc promoter-binding protein; Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. According to PubMed-8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter; DENN/MADD domain containing | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | 0.445 |
DENND4A | COMMD4 | ENSP00000391167 | ENSP00000267935 | C-myc promoter-binding protein; Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. According to PubMed-8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter; DENN/MADD domain containing | COMM domain-containing protein 4; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Down-regulates activation of NF-kappa-B | 0.410 |
DENND4A | OR10J3 | ENSP00000391167 | ENSP00000331789 | C-myc promoter-binding protein; Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. According to PubMed-8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter; DENN/MADD domain containing | Olfactory receptor 10J3; Odorant receptor; Olfactory receptors, family 10 | 0.424 |
GSPT2 | C1orf159 | ENSP00000341247 | ENSP00000400736 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | 0.424 |
OR10J3 | C1orf159 | ENSP00000331789 | ENSP00000400736 | Olfactory receptor 10J3; Odorant receptor; Olfactory receptors, family 10 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159 | 0.530 |