node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BLNK | CMTM3 | ENSP00000224337 | ENSP00000400482 | B-cell linker protein; Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR- media [...] | CKLF like MARVEL transmembrane domain containing 3; Belongs to the chemokine-like factor family | 0.853 |
BLNK | CMTM7 | ENSP00000224337 | ENSP00000335605 | B-cell linker protein; Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR- media [...] | CKLF like MARVEL transmembrane domain containing 7; Belongs to the chemokine-like factor family | 0.632 |
CKLF | CMTM2 | ENSP00000264001 | ENSP00000268595 | Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 | CKLF like MARVEL transmembrane domain containing 2; Belongs to the chemokine-like factor family | 0.905 |
CKLF | CMTM3 | ENSP00000264001 | ENSP00000400482 | Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 | CKLF like MARVEL transmembrane domain containing 3; Belongs to the chemokine-like factor family | 0.910 |
CKLF | CMTM4 | ENSP00000264001 | ENSP00000333833 | Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 | CKLF like MARVEL transmembrane domain containing 4 | 0.906 |
CKLF | CMTM7 | ENSP00000264001 | ENSP00000335605 | Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 | CKLF like MARVEL transmembrane domain containing 7; Belongs to the chemokine-like factor family | 0.903 |
CKLF | CMTM8 | ENSP00000264001 | ENSP00000307741 | Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 | CKLF like MARVEL transmembrane domain containing 8; Belongs to the chemokine-like factor family | 0.800 |
CMTM1 | CMTM3 | ENSP00000368814 | ENSP00000400482 | CKLF like MARVEL transmembrane domain containing 1 | CKLF like MARVEL transmembrane domain containing 3; Belongs to the chemokine-like factor family | 0.905 |
CMTM1 | CMTM4 | ENSP00000368814 | ENSP00000333833 | CKLF like MARVEL transmembrane domain containing 1 | CKLF like MARVEL transmembrane domain containing 4 | 0.905 |
CMTM1 | CMTM7 | ENSP00000368814 | ENSP00000335605 | CKLF like MARVEL transmembrane domain containing 1 | CKLF like MARVEL transmembrane domain containing 7; Belongs to the chemokine-like factor family | 0.800 |
CMTM1 | CMTM8 | ENSP00000368814 | ENSP00000307741 | CKLF like MARVEL transmembrane domain containing 1 | CKLF like MARVEL transmembrane domain containing 8; Belongs to the chemokine-like factor family | 0.564 |
CMTM2 | CKLF | ENSP00000268595 | ENSP00000264001 | CKLF like MARVEL transmembrane domain containing 2; Belongs to the chemokine-like factor family | Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 | 0.905 |
CMTM2 | CMTM3 | ENSP00000268595 | ENSP00000400482 | CKLF like MARVEL transmembrane domain containing 2; Belongs to the chemokine-like factor family | CKLF like MARVEL transmembrane domain containing 3; Belongs to the chemokine-like factor family | 0.905 |
CMTM2 | CMTM4 | ENSP00000268595 | ENSP00000333833 | CKLF like MARVEL transmembrane domain containing 2; Belongs to the chemokine-like factor family | CKLF like MARVEL transmembrane domain containing 4 | 0.905 |
CMTM2 | CMTM7 | ENSP00000268595 | ENSP00000335605 | CKLF like MARVEL transmembrane domain containing 2; Belongs to the chemokine-like factor family | CKLF like MARVEL transmembrane domain containing 7; Belongs to the chemokine-like factor family | 0.800 |
CMTM2 | CMTM8 | ENSP00000268595 | ENSP00000307741 | CKLF like MARVEL transmembrane domain containing 2; Belongs to the chemokine-like factor family | CKLF like MARVEL transmembrane domain containing 8; Belongs to the chemokine-like factor family | 0.511 |
CMTM3 | BLNK | ENSP00000400482 | ENSP00000224337 | CKLF like MARVEL transmembrane domain containing 3; Belongs to the chemokine-like factor family | B-cell linker protein; Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR- media [...] | 0.853 |
CMTM3 | CKLF | ENSP00000400482 | ENSP00000264001 | CKLF like MARVEL transmembrane domain containing 3; Belongs to the chemokine-like factor family | Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 | 0.910 |
CMTM3 | CMTM1 | ENSP00000400482 | ENSP00000368814 | CKLF like MARVEL transmembrane domain containing 3; Belongs to the chemokine-like factor family | CKLF like MARVEL transmembrane domain containing 1 | 0.905 |
CMTM3 | CMTM2 | ENSP00000400482 | ENSP00000268595 | CKLF like MARVEL transmembrane domain containing 3; Belongs to the chemokine-like factor family | CKLF like MARVEL transmembrane domain containing 2; Belongs to the chemokine-like factor family | 0.905 |