• Version:
  • 11.0 [archived version]
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LYRM2 LYRM2 LURAP1L LURAP1L LYRM5 LYRM5 CCDC81 CCDC81 LYRM1 LYRM1 C17orf89 C17orf89 KLHL18 KLHL18 ENTHD2 ENTHD2 TMEM169 TMEM169 C9orf50 C9orf50 SLC38A10 SLC38A10
"C17orf89" - NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
C17orf89NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8; Involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I, MT-ND1). Required to stabilize NDUFAF5 (74 aa)    
Predicted Functional Partners:
LYRM5
Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB) (90 aa)
           
  0.668
CCDC81
Coiled-coil domain containing 81 (652 aa)
           
  0.559
ENTHD2
AP-4 complex accessory subunit Tepsin; Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network (525 aa)
           
  0.558
LYRM1
LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family (122 aa)
           
  0.557
C9orf50
Uncharacterized protein C9orf50; Chromosome 9 open reading frame 50 (431 aa)
           
  0.551
KLHL18
Kelch-like protein 18; Kelch like family member 18; BTB domain containing (574 aa)
           
  0.531
LYRM2
LYR motif containing 2 (88 aa)
           
  0.527
TMEM169
Transmembrane protein 169 (297 aa)
           
  0.527
SLC38A10
Putative sodium-coupled neutral amino acid transporter 10; Putative sodium-dependent amino acid/proton antiporter; Solute carriers (1119 aa)
           
  0.513
LURAP1L
Leucine rich adaptor protein 1 like (228 aa)
           
  0.513
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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