node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARL17B | C12orf73 | ENSP00000404247 | ENSP00000367330 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); ARF GTPase family | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | 0.446 |
ARL17B | CLDND2 | ENSP00000404247 | ENSP00000291715 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); ARF GTPase family | Claudin domain containing 2 | 0.426 |
ARL17B | CRNKL1 | ENSP00000404247 | ENSP00000366557 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); ARF GTPase family | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | 0.428 |
ARL17B | FAM65A | ENSP00000404247 | ENSP00000400099 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); ARF GTPase family | Rho family-interacting cell polarization regulator 1; Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation; Belongs to the RIPOR family | 0.535 |
ARL17B | LY6G5C | ENSP00000404247 | ENSP00000372724 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); ARF GTPase family | Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation; LY6/PLAUR domain containing | 0.440 |
ARL17B | R3HDM2 | ENSP00000404247 | ENSP00000317903 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); ARF GTPase family | R3H domain containing 2 | 0.546 |
C12orf73 | ARL17B | ENSP00000367330 | ENSP00000404247 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); ARF GTPase family | 0.446 |
C12orf73 | CLDND2 | ENSP00000367330 | ENSP00000291715 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | Claudin domain containing 2 | 0.587 |
C12orf73 | CRNKL1 | ENSP00000367330 | ENSP00000366557 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | 0.441 |
C12orf73 | FAM65A | ENSP00000367330 | ENSP00000400099 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | Rho family-interacting cell polarization regulator 1; Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation; Belongs to the RIPOR family | 0.557 |
C12orf73 | LY6G5C | ENSP00000367330 | ENSP00000372724 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation; LY6/PLAUR domain containing | 0.470 |
C12orf73 | NAA20 | ENSP00000367330 | ENSP00000335636 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | N-alpha-acetyltransferase 20; Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration; Belongs to the acetyltransferase family. ARD1 subfamily | 0.420 |
C12orf73 | R3HDM2 | ENSP00000367330 | ENSP00000317903 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | R3H domain containing 2 | 0.491 |
CLDND2 | ARL17B | ENSP00000291715 | ENSP00000404247 | Claudin domain containing 2 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); ARF GTPase family | 0.426 |
CLDND2 | C12orf73 | ENSP00000291715 | ENSP00000367330 | Claudin domain containing 2 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | 0.587 |
CLDND2 | CRNKL1 | ENSP00000291715 | ENSP00000366557 | Claudin domain containing 2 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | 0.420 |
CLDND2 | FAM65A | ENSP00000291715 | ENSP00000400099 | Claudin domain containing 2 | Rho family-interacting cell polarization regulator 1; Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation; Belongs to the RIPOR family | 0.536 |
CLDND2 | LY6G5C | ENSP00000291715 | ENSP00000372724 | Claudin domain containing 2 | Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation; LY6/PLAUR domain containing | 0.440 |
CLDND2 | R3HDM2 | ENSP00000291715 | ENSP00000317903 | Claudin domain containing 2 | R3H domain containing 2 | 0.473 |
CRNKL1 | ARL17B | ENSP00000366557 | ENSP00000404247 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); ARF GTPase family | 0.428 |