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STRINGSTRING
MAB21L1 MAB21L1 FAM186A FAM186A NSMCE4A NSMCE4A TEX13B TEX13B NBEAL1 NBEAL1 MAB21L2 MAB21L2 TRIM47 TRIM47 ZBTB44 ZBTB44 SERTAD4 SERTAD4 PTPN4 PTPN4 YPEL2 YPEL2
"NBEAL1" - Neurobeachin-like protein 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
NBEAL1Neurobeachin-like protein 1; Armadillo-like helical domain containing; Belongs to the WD repeat neurobeachin family (2694 aa)    
Predicted Functional Partners:
YPEL2
Protein yippee-like 2; Yippee like family (119 aa)
      
   
  0.740
ZBTB44
Zinc finger and BTB domain-containing protein 44; May be involved in transcriptional regulation; BTB domain containing (570 aa)
      
   
  0.725
SERTAD4
SERTA domain containing 4 (356 aa)
            
  0.717
PTPN4
Tyrosine-protein phosphatase non-receptor type 4; May act at junctions between the membrane and the cytoskeleton; Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily (926 aa)
      
   
  0.662
TEX13B
Testis-expressed protein 13B; Testis expressed 13B; Belongs to the TEX13 family (312 aa)
            
  0.571
TRIM47
Tripartite motif containing 47; Ring finger proteins (638 aa)
      
   
  0.533
MAB21L2
Protein mab-21-like 2; Required for several aspects of embryonic development including normal development of the eye; Belongs to the mab-21 family (359 aa)
            
  0.515
MAB21L1
Putative nucleotidyltransferase MAB21L1; Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye (By similarity). It is unclear whether it displays nucleotidyltransferase activity in vivo. Binds single-stranded RNA (ssRNA) (359 aa)
            
  0.493
NSMCE4A
Non-structural maintenance of chromosomes element 4 homolog A; Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies ( [...] (385 aa)
            
  0.477
FAM186A
Protein FAM186A; Family with sequence similarity 186 member A; Belongs to the FAM186 family (2351 aa)
            
  0.477
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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