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  • 11.0 [archived version]
STRINGSTRING
SPON1 SPON1 C16orf90 C16orf90 TECRL TECRL MLC1 MLC1 C3orf52 C3orf52 SEPT14 SEPT14 ZNF343 ZNF343 C4orf19 C4orf19 SLC25A29 SLC25A29 CLVS2 CLVS2 SLC17A3 SLC17A3
"C3orf52" - TPA-induced transmembrane protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
C3orf52TPA-induced transmembrane protein; Chromosome 3 open reading frame 52 (250 aa)    
Predicted Functional Partners:
TECRL
trans-2,3-enoyl-CoA reductase like (363 aa)
           
  0.714
CLVS2
Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (327 aa)
           
  0.698
SPON1
Spondin-1; Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell (807 aa)
           
  0.640
C16orf90
Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90 (182 aa)
           
  0.588
C4orf19
Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 (314 aa)
           
  0.581
SLC25A29
Mitochondrial basic amino acids transporter; Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. Can restore ornithine transport in cells lacking the primary mitochondrial ornithine transporter SLC25A15. Does not transport carnitine nor acylcarnitines. Functions by both counter- exchange and uniport mechanisms; Solute carriers (303 aa)
           
  0.559
SEPT14
Septin-14; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Septins (432 aa)
           
  0.551
MLC1
Membrane protein MLC1; Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx (377 aa)
           
  0.548
SLC17A3
Sodium-dependent phosphate transport protein 4; Isoform 2- voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+) cotransport; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family (498 aa)
           
  0.530
ZNF343
Zinc finger protein 343; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (640 aa)
           
  0.530
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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