SLC6A12 protein (human) - STRING database

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SLC6A12

Sodium- and chloride-dependent betaine transporter; Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation; Solute carriers (614 aa)

Predicted Functional Partners:

GATS

0.851

SLC5A3

0.781

GAD1

0.693

SLC29A3

0.679

GABRR3

0.673

NFAT5

0.669

SLC15A1

0.668

SLC22A16

0.668

GAD2

0.658

SLC32A1

0.657

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GABRR3	GAD1	ENSP00000481321	ENSP00000350928	Gamma-aminobutyric acid receptor subunit rho-3; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	0.839
GABRR3	GAD2	ENSP00000481321	ENSP00000365437	Gamma-aminobutyric acid receptor subunit rho-3; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits	Glutamate decarboxylase 2; Catalyzes the production of GABA	0.801
GABRR3	GATS	ENSP00000481321	ENSP00000389760	Gamma-aminobutyric acid receptor subunit rho-3; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits	Putative protein GATS; GATS, stromal antigen 3 opposite strand; Belongs to the GATS family	0.669
GABRR3	SLC32A1	ENSP00000481321	ENSP00000217420	Gamma-aminobutyric acid receptor subunit rho-3; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits	Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Solute carriers	0.735
GABRR3	SLC6A12	ENSP00000481321	ENSP00000399136	Gamma-aminobutyric acid receptor subunit rho-3; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits	Sodium- and chloride-dependent betaine transporter; Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation; Solute carriers	0.673
GAD1	GABRR3	ENSP00000350928	ENSP00000481321	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Gamma-aminobutyric acid receptor subunit rho-3; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits	0.839
GAD1	GAD2	ENSP00000350928	ENSP00000365437	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Glutamate decarboxylase 2; Catalyzes the production of GABA	0.956
GAD1	GATS	ENSP00000350928	ENSP00000389760	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Putative protein GATS; GATS, stromal antigen 3 opposite strand; Belongs to the GATS family	0.566
GAD1	SLC32A1	ENSP00000350928	ENSP00000217420	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Solute carriers	0.999
GAD1	SLC6A12	ENSP00000350928	ENSP00000399136	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	Sodium- and chloride-dependent betaine transporter; Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation; Solute carriers	0.693
GAD2	GABRR3	ENSP00000365437	ENSP00000481321	Glutamate decarboxylase 2; Catalyzes the production of GABA	Gamma-aminobutyric acid receptor subunit rho-3; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits	0.801
GAD2	GAD1	ENSP00000365437	ENSP00000350928	Glutamate decarboxylase 2; Catalyzes the production of GABA	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	0.956
GAD2	GATS	ENSP00000365437	ENSP00000389760	Glutamate decarboxylase 2; Catalyzes the production of GABA	Putative protein GATS; GATS, stromal antigen 3 opposite strand; Belongs to the GATS family	0.591
GAD2	SLC32A1	ENSP00000365437	ENSP00000217420	Glutamate decarboxylase 2; Catalyzes the production of GABA	Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Solute carriers	0.994
GAD2	SLC6A12	ENSP00000365437	ENSP00000399136	Glutamate decarboxylase 2; Catalyzes the production of GABA	Sodium- and chloride-dependent betaine transporter; Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation; Solute carriers	0.658
GATS	GABRR3	ENSP00000389760	ENSP00000481321	Putative protein GATS; GATS, stromal antigen 3 opposite strand; Belongs to the GATS family	Gamma-aminobutyric acid receptor subunit rho-3; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits	0.669
GATS	GAD1	ENSP00000389760	ENSP00000350928	Putative protein GATS; GATS, stromal antigen 3 opposite strand; Belongs to the GATS family	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family	0.566
GATS	GAD2	ENSP00000389760	ENSP00000365437	Putative protein GATS; GATS, stromal antigen 3 opposite strand; Belongs to the GATS family	Glutamate decarboxylase 2; Catalyzes the production of GABA	0.591
GATS	SLC32A1	ENSP00000389760	ENSP00000217420	Putative protein GATS; GATS, stromal antigen 3 opposite strand; Belongs to the GATS family	Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Solute carriers	0.612
GATS	SLC6A12	ENSP00000389760	ENSP00000399136	Putative protein GATS; GATS, stromal antigen 3 opposite strand; Belongs to the GATS family	Sodium- and chloride-dependent betaine transporter; Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation; Solute carriers	0.851

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