• Version:
  • 11.0 [archived version]
STRINGSTRING
ANXA7 ANXA7 SERPINE2 SERPINE2 AGR3 AGR3 FERD3L FERD3L ANKMY2 ANKMY2 SNX13 SNX13 TSPAN13 TSPAN13 BZW2 BZW2 RER1 RER1 HEPACAM2 HEPACAM2 RPP25L RPP25L
"SNX13" - Sorting nexin-13 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
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[Homology]
Score
SNX13Sorting nexin-13; May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis (By similarity). Acts as a GAP for Galphas; Belongs to the sorting nexin family (957 aa)    
Predicted Functional Partners:
BZW2
Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation (419 aa)
           
  0.825
ANKMY2
Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia; Ankyrin repeat domain containing (441 aa)
     
   
  0.815
RPP25L
Ribonuclease P protein subunit p25-like protein; May be a component of ribonuclease P or MRP (163 aa)
     
   
  0.806
FERD3L
Fer3-like protein; Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins (By similarity); Basic helix-loop-helix proteins (166 aa)
           
  0.794
ANXA7
Annexin A7; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis; Belongs to the annexin family (488 aa)
           
  0.754
HEPACAM2
HEPACAM family member 2; Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes- anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation; I-set domain containing (485 aa)
           
  0.736
AGR3
Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family (166 aa)
           
  0.716
TSPAN13
Tetraspanin-13; Tetraspanin 13; Tetraspanins (204 aa)
           
  0.704
RER1
Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment (196 aa)
     
   
  0.702
SERPINE2
Glia-derived nexin; Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin; Belongs to the serpin family (409 aa)
           
  0.641
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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