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  • 11.0 [archived version]
STRINGSTRING
TBCD TBCD TBCE TBCE URI1 URI1 CACNA1E CACNA1E ARL13A ARL13A TEX13A TEX13A ARL16 ARL16 AFF2 AFF2 ARL9 ARL9 CYLC1 CYLC1 KIF17 KIF17
"ARL13A" - ADP-ribosylation factor-like protein 13A in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ARL13AADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A; ARF GTPase family (256 aa)    
Predicted Functional Partners:
TBCD
Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epi [...] (1192 aa)
     
 
  0.855
ARL9
ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family (123 aa)
           
  0.733
URI1
Unconventional prefoldin RPB5 interactor 1; Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein; Belongs to the RNA polymerase II subunit [...] (535 aa)
     
   
  0.695
CYLC1
Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation (651 aa)
           
  0.686
ARL16
ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16; ARF GTPase family (197 aa)
           
  0.668
AFF2
AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure; AF4/FMR2 family (1311 aa)
           
  0.666
CACNA1E
Voltage-dependent R-type calcium channel subunit alpha-1E; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the ’high-voltage activated’ (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insens [...] (2313 aa)
     
   
  0.639
TEX13A
Testis-expressed protein 13A; Zinc fingers RANBP2-type ; Belongs to the TEX13 family (409 aa)
     
   
  0.633
TBCE
Tubulin-specific chaperone E; Tubulin-folding protein; involved in the second step of the tubulin folding pathway and in the regulation of tubulin heterodimer dissociation. Required for correct organization of microtubule cytoskeleton and mitotic splindle, and maintenance of the neuronal microtubule network (578 aa)
     
 
  0.623
KIF17
Kinesin-like protein KIF17; Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family (1029 aa)
     
 
  0.595
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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