• Version:
  • 11.0 [archived version]
STRINGSTRING
OR2F1 OR2F1 ZNF812 ZNF812 FAM151B FAM151B TMEM243 TMEM243 DMTF1 DMTF1 ACRBP ACRBP RUNDC3B RUNDC3B DBF4 DBF4 SLC25A40 SLC25A40 CROT CROT ZNF653 ZNF653
"TMEM243" - Transmembrane protein 243 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM243Transmembrane protein 243; Belongs to the TMEM243 family (118 aa)    
Predicted Functional Partners:
RUNDC3B
RUN domain containing 3B (473 aa)
           
  0.721
DMTF1
Cyclin-D-binding Myb-like transcription factor 1; Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest (By similarity). Binds to the consensus sequence 5’-CCCG[GT]ATGT-3’ (By similarity). Isoform 1 may cooperate with MYB to activate transcription of the ANPEP gene. Isoform 2 may antagonize transcriptional activation by isoform 1; Myb/SANT domain containing (760 aa)
     
   
  0.651
SLC25A40
Solute carrier family 25 member 40 (338 aa)
           
  0.641
ACRBP
Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin; Armadillo-like helical domain containing (543 aa)
           
  0.500
ZNF653
Zinc finger protein 653; Transcriptional repressor. May repress NR5A1, PPARG, NR1H3, NR4A2, ESR1 and NR3C1 transcriptional activity; Zinc fingers C2H2-type (615 aa)
           
  0.499
DBF4
Protein DBF4 homolog A; Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at ’Ser-40’ and ’Ser-53’ and then is involved in regulating the initiation of DNA replication during cell cycle; Zinc fingers DBF-type (674 aa)
           
  0.485
CROT
Peroxisomal carnitine O-octanoyltransferase; Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl- CoA, to its corresponding carnitine ester; Belongs to the carnitine/choline acetyltransferase family (640 aa)
           
  0.474
OR2F1
Olfactory receptor 2F1; Odorant receptor; Olfactory receptors, family 2 (317 aa)
           
  0.473
FAM151B
Protein FAM151B; Family with sequence similarity 151 member B (276 aa)
           
  0.473
ZNF812
Zinc finger protein 812 (454 aa)
           
  0.445
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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