• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM212A FAM212A ADAM30 ADAM30 ZFYVE16 ZFYVE16 ARID4A ARID4A TRIM28 TRIM28 ANKRA2 ANKRA2 ZNF697 ZNF697 ZZZ3 ZZZ3 PYROXD1 PYROXD1 ZNF608 ZNF608 ZBED4 ZBED4
"ZNF697" - Zinc finger protein 697 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF697Zinc finger protein 697; May be involved in transcriptional regulation; Zinc fingers C2H2-type (545 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.903
ZZZ3
ZZ-type zinc finger-containing protein 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (903 aa)
           
  0.596
ZFYVE16
Zinc finger FYVE domain-containing protein 16; May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes; Protein phosphatase 1 regulatory subunits (1539 aa)
           
  0.584
ANKRA2
Ankyrin repeat family A protein 2; May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5. May also regulate LRP2/megalin (By similarity); Ankyrin repeat domain containing (313 aa)
     
 
  0.567
ZNF608
Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription; Zinc fingers C2H2-type (1512 aa)
           
  0.561
ADAM30
Disintegrin and metalloproteinase domain-containing protein 30; Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation; ADAM metallopeptidase domain containing (790 aa)
           
  0.555
FAM212A
PAK4-inhibitor INKA1; Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity (287 aa)
           
  0.478
ARID4A
AT-rich interactive domain-containing protein 4A; Interacts with the viral protein-binding domain of the retinoblastoma protein; AT-rich interaction domain containing (1257 aa)
       
 
  0.469
PYROXD1
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily (500 aa)
       
 
  0.431
ZBED4
Zinc finger BED-type containing 4 (1171 aa)
       
 
  0.431
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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