ANKRD60 protein (human) - STRING database

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ANKRD60

Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing (345 aa)

Predicted Functional Partners:

GRAMD1B

0.751

C4orf22

0.681

FAM132A

0.626

ZNF521

0.625

ANKRD35

0.583

CNDP1

0.545

GPR125

0.543

KBTBD8

0.533

SUPT3H

0.511

NUP37

0.496

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD35	ANKRD60	ENSP00000347802	ENSP00000396747	Ankyrin repeat domain-containing protein 35; Ankyrin repeat domain containing	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	0.583
ANKRD60	ANKRD35	ENSP00000396747	ENSP00000347802	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	Ankyrin repeat domain-containing protein 35; Ankyrin repeat domain containing	0.583
ANKRD60	C4orf22	ENSP00000396747	ENSP00000425786	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	Uncharacterized protein C4orf22; Chromosome 4 open reading frame 22	0.681
ANKRD60	CNDP1	ENSP00000396747	ENSP00000351682	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	Carnosine dipeptidase 1; Belongs to the peptidase M20A family	0.545
ANKRD60	FAM132A	ENSP00000396747	ENSP00000329137	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	Adipolin; Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue	0.626
ANKRD60	GPR125	ENSP00000396747	ENSP00000334952	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	0.543
ANKRD60	GRAMD1B	ENSP00000396747	ENSP00000402457	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	GRAM domain containing 1B	0.751
ANKRD60	KBTBD8	ENSP00000396747	ENSP00000401878	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	Kelch repeat and BTB domain-containing protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1- monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification; BTB domain containing	0.533
ANKRD60	NUP37	ENSP00000396747	ENSP00000448054	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	Nucleoporin Nup37; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation; Nucleoporins	0.496
ANKRD60	SUPT3H	ENSP00000396747	ENSP00000360515	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	Transcription initiation protein SPT3 homolog; Probable transcriptional activator; SAGA complex	0.511
ANKRD60	ZNF521	ENSP00000396747	ENSP00000354794	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	Zinc finger protein 521; Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes; Belongs to the krueppel C2H2-type zinc-finger protein family	0.625
C4orf22	ANKRD60	ENSP00000425786	ENSP00000396747	Uncharacterized protein C4orf22; Chromosome 4 open reading frame 22	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	0.681
C4orf22	GPR125	ENSP00000425786	ENSP00000334952	Uncharacterized protein C4orf22; Chromosome 4 open reading frame 22	Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	0.520
C4orf22	GRAMD1B	ENSP00000425786	ENSP00000402457	Uncharacterized protein C4orf22; Chromosome 4 open reading frame 22	GRAM domain containing 1B	0.502
CNDP1	ANKRD60	ENSP00000351682	ENSP00000396747	Carnosine dipeptidase 1; Belongs to the peptidase M20A family	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	0.545
CNDP1	FAM132A	ENSP00000351682	ENSP00000329137	Carnosine dipeptidase 1; Belongs to the peptidase M20A family	Adipolin; Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue	0.493
FAM132A	ANKRD60	ENSP00000329137	ENSP00000396747	Adipolin; Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	0.626
FAM132A	CNDP1	ENSP00000329137	ENSP00000351682	Adipolin; Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue	Carnosine dipeptidase 1; Belongs to the peptidase M20A family	0.493
GPR125	ANKRD60	ENSP00000334952	ENSP00000396747	Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Ankyrin repeat domain-containing protein 60; Ankyrin repeat domain containing	0.543
GPR125	C4orf22	ENSP00000334952	ENSP00000425786	Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Uncharacterized protein C4orf22; Chromosome 4 open reading frame 22	0.520

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