MROH7 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MROH7

Maestro heat like repeat family member 7 (1323 aa)

Predicted Functional Partners:

HEATR4

0.660

FAM179A

0.609

TANGO6

0.583

RTDR1

0.582

KIAA1468

0.527

KPNB1

0.525

INTS4

0.517

HEATR2

0.510

MRO

0.473

TTC4

0.455

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM179A	HEATR2	ENSP00000368876	ENSP00000297440	TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A	Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility	0.646
FAM179A	HEATR4	ENSP00000368876	ENSP00000450444	TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A	HEAT repeat-containing protein 4; Armadillo-like helical domain containing	0.740
FAM179A	INTS4	ENSP00000368876	ENSP00000434466	TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A	Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex; Armadillo-like helical domain containing	0.734
FAM179A	KIAA1468	ENSP00000368876	ENSP00000381198	TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A	LisH domain and HEAT repeat-containing protein KIAA1468; Armadillo-like helical domain containing	0.741
FAM179A	MROH7	ENSP00000368876	ENSP00000396622	TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A	Maestro heat like repeat family member 7	0.609
FAM179A	RTDR1	ENSP00000368876	ENSP00000216036	TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A	Radial spoke head 14 homolog; Rhabdoid tumor deletion region gene 1; Belongs to the flagellar radial spoke RSP14 family	0.728
FAM179A	TANGO6	ENSP00000368876	ENSP00000261778	TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A	Transport and golgi organization 6 homolog; Armadillo-like helical domain containing	0.768
HEATR2	FAM179A	ENSP00000297440	ENSP00000368876	Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility	TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A	0.646
HEATR2	HEATR4	ENSP00000297440	ENSP00000450444	Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility	HEAT repeat-containing protein 4; Armadillo-like helical domain containing	0.641
HEATR2	INTS4	ENSP00000297440	ENSP00000434466	Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility	Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex; Armadillo-like helical domain containing	0.613
HEATR2	KIAA1468	ENSP00000297440	ENSP00000381198	Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility	LisH domain and HEAT repeat-containing protein KIAA1468; Armadillo-like helical domain containing	0.617
HEATR2	MROH7	ENSP00000297440	ENSP00000396622	Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility	Maestro heat like repeat family member 7	0.510
HEATR2	RTDR1	ENSP00000297440	ENSP00000216036	Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility	Radial spoke head 14 homolog; Rhabdoid tumor deletion region gene 1; Belongs to the flagellar radial spoke RSP14 family	0.641
HEATR2	TANGO6	ENSP00000297440	ENSP00000261778	Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility	Transport and golgi organization 6 homolog; Armadillo-like helical domain containing	0.664
HEATR4	FAM179A	ENSP00000450444	ENSP00000368876	HEAT repeat-containing protein 4; Armadillo-like helical domain containing	TOG array regulator of axonemal microtubules protein 2; Family with sequence similarity 179, member A	0.740
HEATR4	HEATR2	ENSP00000450444	ENSP00000297440	HEAT repeat-containing protein 4; Armadillo-like helical domain containing	Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility	0.641
HEATR4	INTS4	ENSP00000450444	ENSP00000434466	HEAT repeat-containing protein 4; Armadillo-like helical domain containing	Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex; Armadillo-like helical domain containing	0.660
HEATR4	KIAA1468	ENSP00000450444	ENSP00000381198	HEAT repeat-containing protein 4; Armadillo-like helical domain containing	LisH domain and HEAT repeat-containing protein KIAA1468; Armadillo-like helical domain containing	0.698
HEATR4	MROH7	ENSP00000450444	ENSP00000396622	HEAT repeat-containing protein 4; Armadillo-like helical domain containing	Maestro heat like repeat family member 7	0.660
HEATR4	RTDR1	ENSP00000450444	ENSP00000216036	HEAT repeat-containing protein 4; Armadillo-like helical domain containing	Radial spoke head 14 homolog; Rhabdoid tumor deletion region gene 1; Belongs to the flagellar radial spoke RSP14 family	0.721

page 1 of 4

Network

Fusion

Experiments

Cooccurrence

Textmining

Coexpression

Databases

Neighborhood

© STRING Consortium 2020

Credits

Access

Info

About