| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAM23 | DSCR3 | ENSP00000264377 | ENSP00000311399 | Disintegrin and metalloproteinase domain-containing protein 23; May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing | Down syndrome critical region gene 3; Belongs to the VPS26 family | 0.672 |
| ADAM23 | DYTN | ENSP00000264377 | ENSP00000396593 | Disintegrin and metalloproteinase domain-containing protein 23; May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing | Dystrotelin; Zinc fingers ZZ-type | 0.537 |
| ADAM23 | RAB11FIP4 | ENSP00000264377 | ENSP00000482620 | Disintegrin and metalloproteinase domain-containing protein 23; May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing | Rab11 family-interacting protein 4; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an ’address tag’ delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6; EF-hand domain containing | 0.657 |
| DPP3 | DYTN | ENSP00000353701 | ENSP00000396593 | Dipeptidyl peptidase 3; Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin. Also cleaves Arg-Arg-beta-naphthylamide (in vitro); Belongs to the peptidase M49 family | Dystrotelin; Zinc fingers ZZ-type | 0.572 |
| DSCR3 | ADAM23 | ENSP00000311399 | ENSP00000264377 | Down syndrome critical region gene 3; Belongs to the VPS26 family | Disintegrin and metalloproteinase domain-containing protein 23; May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing | 0.672 |
| DSCR3 | DYTN | ENSP00000311399 | ENSP00000396593 | Down syndrome critical region gene 3; Belongs to the VPS26 family | Dystrotelin; Zinc fingers ZZ-type | 0.715 |
| DSCR3 | RAB11FIP4 | ENSP00000311399 | ENSP00000482620 | Down syndrome critical region gene 3; Belongs to the VPS26 family | Rab11 family-interacting protein 4; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an ’address tag’ delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6; EF-hand domain containing | 0.646 |
| DYTN | ADAM23 | ENSP00000396593 | ENSP00000264377 | Dystrotelin; Zinc fingers ZZ-type | Disintegrin and metalloproteinase domain-containing protein 23; May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing | 0.537 |
| DYTN | DPP3 | ENSP00000396593 | ENSP00000353701 | Dystrotelin; Zinc fingers ZZ-type | Dipeptidyl peptidase 3; Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin. Also cleaves Arg-Arg-beta-naphthylamide (in vitro); Belongs to the peptidase M49 family | 0.572 |
| DYTN | DSCR3 | ENSP00000396593 | ENSP00000311399 | Dystrotelin; Zinc fingers ZZ-type | Down syndrome critical region gene 3; Belongs to the VPS26 family | 0.715 |
| DYTN | FASTKD2 | ENSP00000396593 | ENSP00000236980 | Dystrotelin; Zinc fingers ZZ-type | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit; FASTK mitochondrial RNA binding family | 0.649 |
| DYTN | HSPBP1 | ENSP00000396593 | ENSP00000255631 | Dystrotelin; Zinc fingers ZZ-type | Hsp70-binding protein 1; Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR; Armadillo-like helical domain containing | 0.644 |
| DYTN | LRRC38 | ENSP00000396593 | ENSP00000365253 | Dystrotelin; Zinc fingers ZZ-type | Leucine-rich repeat-containing protein 38; Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel’s voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium | 0.533 |
| DYTN | MDH1B | ENSP00000396593 | ENSP00000363533 | Dystrotelin; Zinc fingers ZZ-type | Malate dehydrogenase 1B | 0.527 |
| DYTN | OR3A2 | ENSP00000396593 | ENSP00000386180 | Dystrotelin; Zinc fingers ZZ-type | Olfactory receptor 3A2; Odorant receptor; Olfactory receptors, family 3 | 0.585 |
| DYTN | RAB11FIP3 | ENSP00000396593 | ENSP00000262305 | Dystrotelin; Zinc fingers ZZ-type | Rab11 family-interacting protein 3; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an ’address tag’ delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive [...] | 0.744 |
| DYTN | RAB11FIP4 | ENSP00000396593 | ENSP00000482620 | Dystrotelin; Zinc fingers ZZ-type | Rab11 family-interacting protein 4; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an ’address tag’ delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6; EF-hand domain containing | 0.784 |
| FASTKD2 | DYTN | ENSP00000236980 | ENSP00000396593 | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit; FASTK mitochondrial RNA binding family | Dystrotelin; Zinc fingers ZZ-type | 0.649 |
| HSPBP1 | DYTN | ENSP00000255631 | ENSP00000396593 | Hsp70-binding protein 1; Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR; Armadillo-like helical domain containing | Dystrotelin; Zinc fingers ZZ-type | 0.644 |
| LRRC38 | DYTN | ENSP00000365253 | ENSP00000396593 | Leucine-rich repeat-containing protein 38; Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel’s voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium | Dystrotelin; Zinc fingers ZZ-type | 0.533 |
