• Version:
  • 11.0 [archived version]
STRINGSTRING
PEAR1 PEAR1 GPATCH4 GPATCH4 DDX55 DDX55 FTSJ3 FTSJ3 BYSL BYSL WDR46 WDR46 RBM28 RBM28 PES1 PES1 DDX54 DDX54 MAK16 MAK16 RPF2 RPF2
"GPATCH4" - G-patch domain containing 4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
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Textmining
[Homology]
Score
GPATCH4G-patch domain containing 4 (375 aa)    
Predicted Functional Partners:
DDX55
ATP-dependent RNA helicase DDX55; Probable ATP-binding RNA helicase; DEAD-box helicases (600 aa)
     
 
  0.849
MAK16
Protein MAK16 homolog; RNA binding motif containing (300 aa)
     
      0.845
BYSL
Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos; Belongs to the bystin family (437 aa)
     
      0.795
DDX54
ATP-dependent RNA helicase DDX54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors; DEAD-box helicases (882 aa)
     
 
  0.794
RPF2
Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus (306 aa)
     
 
  0.759
FTSJ3
pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily (847 aa)
     
      0.734
PEAR1
Platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells; Belongs to the MEGF family (1037 aa)
           
  0.724
PES1
Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family (588 aa)
     
        0.716
RBM28
RNA-binding protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes; RNA binding motif containing (759 aa)
     
      0.702
WDR46
WD repeat-containing protein 46; Scaffold component of the nucleolar structure. Required for localization of DDX21 and NCL to the granular compartment of the nucleolus; WD repeat domain containing (610 aa)
     
      0.700
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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