node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARSF | IL1RAPL1 | ENSP00000370519 | ENSP00000368278 | Arylsulfatase F; Sulfatases | Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family | 0.518 |
ARSF | MAP3K15 | ENSP00000370519 | ENSP00000345629 | Arylsulfatase F; Sulfatases | Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily | 0.574 |
ARSF | MAP7D3 | ENSP00000370519 | ENSP00000318086 | Arylsulfatase F; Sulfatases | MAP7 domain-containing protein 3; Promotes the assembly and stability of microtubules | 0.516 |
ARSF | SYTL5 | ENSP00000370519 | ENSP00000395220 | Arylsulfatase F; Sulfatases | Synaptotagmin-like protein 5; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids; Synaptotagmin like tandem C2 proteins | 0.607 |
EXPH5 | RAB27A | ENSP00000265843 | ENSP00000379601 | Exophilin-5; May act as Rab effector protein and play a role in vesicle trafficking | Ras-related protein Rab-27A; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse; RAB, member RAS oncogene GTPases | 0.904 |
EXPH5 | RAB27B | ENSP00000265843 | ENSP00000262094 | Exophilin-5; May act as Rab effector protein and play a role in vesicle trafficking | Ras-related protein Rab-27B; May be involved in targeting uroplakins to urothelial apical membranes; RAB, member RAS oncogene GTPases | 0.602 |
EXPH5 | SYTL5 | ENSP00000265843 | ENSP00000395220 | Exophilin-5; May act as Rab effector protein and play a role in vesicle trafficking | Synaptotagmin-like protein 5; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids; Synaptotagmin like tandem C2 proteins | 0.565 |
EXPH5 | UNC13D | ENSP00000265843 | ENSP00000207549 | Exophilin-5; May act as Rab effector protein and play a role in vesicle trafficking | Protein unc-13 homolog D; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells; UNC13 homologs | 0.474 |
IL1RAPL1 | ARSF | ENSP00000368278 | ENSP00000370519 | Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family | Arylsulfatase F; Sulfatases | 0.518 |
IL1RAPL1 | MAP3K15 | ENSP00000368278 | ENSP00000345629 | Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family | Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily | 0.482 |
IL1RAPL1 | MAP7D3 | ENSP00000368278 | ENSP00000318086 | Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family | MAP7 domain-containing protein 3; Promotes the assembly and stability of microtubules | 0.501 |
IL1RAPL1 | SYTL5 | ENSP00000368278 | ENSP00000395220 | Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family | Synaptotagmin-like protein 5; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids; Synaptotagmin like tandem C2 proteins | 0.565 |
MAP3K15 | ARSF | ENSP00000345629 | ENSP00000370519 | Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily | Arylsulfatase F; Sulfatases | 0.574 |
MAP3K15 | IL1RAPL1 | ENSP00000345629 | ENSP00000368278 | Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily | Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family | 0.482 |
MAP3K15 | MAP7D3 | ENSP00000345629 | ENSP00000318086 | Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily | MAP7 domain-containing protein 3; Promotes the assembly and stability of microtubules | 0.463 |
MAP3K15 | SYTL5 | ENSP00000345629 | ENSP00000395220 | Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily | Synaptotagmin-like protein 5; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids; Synaptotagmin like tandem C2 proteins | 0.571 |
MAP7D3 | ARSF | ENSP00000318086 | ENSP00000370519 | MAP7 domain-containing protein 3; Promotes the assembly and stability of microtubules | Arylsulfatase F; Sulfatases | 0.516 |
MAP7D3 | IL1RAPL1 | ENSP00000318086 | ENSP00000368278 | MAP7 domain-containing protein 3; Promotes the assembly and stability of microtubules | Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family | 0.501 |
MAP7D3 | MAP3K15 | ENSP00000318086 | ENSP00000345629 | MAP7 domain-containing protein 3; Promotes the assembly and stability of microtubules | Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily | 0.463 |
MAP7D3 | SYTL5 | ENSP00000318086 | ENSP00000395220 | MAP7 domain-containing protein 3; Promotes the assembly and stability of microtubules | Synaptotagmin-like protein 5; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids; Synaptotagmin like tandem C2 proteins | 0.552 |