TMEM182 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TMEM182

Transmembrane protein 182 (229 aa)

Predicted Functional Partners:

TM6SF1

0.748

TSPAN33

0.675

LMOD3

0.607

UBQLN3

0.589

ZNF738

0.570

MCTP2

0.557

SMIM23

0.531

CDH15

0.524

ZMAT4

0.521

NXPH1

0.512

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH15	TM6SF1	ENSP00000289746	ENSP00000317000	Cadherin-15; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation	Transmembrane 6 superfamily member 1; May function as sterol isomerase; Belongs to the TM6SF family	0.575
CDH15	TMEM182	ENSP00000289746	ENSP00000394178	Cadherin-15; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation	Transmembrane protein 182	0.524
LMOD3	MCTP2	ENSP00000414670	ENSP00000350377	Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization; Belongs to the tropomodulin family	Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Multiple C2 and transmembrane domain containing	0.489
LMOD3	TMEM182	ENSP00000414670	ENSP00000394178	Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization; Belongs to the tropomodulin family	Transmembrane protein 182	0.607
MCTP2	LMOD3	ENSP00000350377	ENSP00000414670	Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Multiple C2 and transmembrane domain containing	Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization; Belongs to the tropomodulin family	0.489
MCTP2	TMEM182	ENSP00000350377	ENSP00000394178	Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Multiple C2 and transmembrane domain containing	Transmembrane protein 182	0.557
NXPH1	TMEM182	ENSP00000384551	ENSP00000394178	Neurexophilin-1; May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors	Transmembrane protein 182	0.512
NXPH1	UBQLN3	ENSP00000384551	ENSP00000347997	Neurexophilin-1; May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors	Ubiquilin-3; Ubiquilin family	0.504
NXPH1	ZMAT4	ENSP00000384551	ENSP00000297737	Neurexophilin-1; May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors	Zinc finger matrin-type 4	0.524
SMIM23	TMEM182	ENSP00000331214	ENSP00000394178	Small integral membrane protein 23	Transmembrane protein 182	0.531
SMIM23	UBQLN3	ENSP00000331214	ENSP00000347997	Small integral membrane protein 23	Ubiquilin-3; Ubiquilin family	0.478
TM6SF1	CDH15	ENSP00000317000	ENSP00000289746	Transmembrane 6 superfamily member 1; May function as sterol isomerase; Belongs to the TM6SF family	Cadherin-15; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation	0.575
TM6SF1	TMEM182	ENSP00000317000	ENSP00000394178	Transmembrane 6 superfamily member 1; May function as sterol isomerase; Belongs to the TM6SF family	Transmembrane protein 182	0.748
TM6SF1	TSPAN33	ENSP00000317000	ENSP00000483872	Transmembrane 6 superfamily member 1; May function as sterol isomerase; Belongs to the TM6SF family	Tetraspanin-33; Plays an important role in normal erythropoiesis (By similarity). It has a role in the differentiation of erythroid progenitors (By similarity). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity; Belongs to the tetraspanin (TM4SF) family	0.646
TMEM182	CDH15	ENSP00000394178	ENSP00000289746	Transmembrane protein 182	Cadherin-15; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation	0.524
TMEM182	LMOD3	ENSP00000394178	ENSP00000414670	Transmembrane protein 182	Leiomodin-3; Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization; Belongs to the tropomodulin family	0.607
TMEM182	MCTP2	ENSP00000394178	ENSP00000350377	Transmembrane protein 182	Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Multiple C2 and transmembrane domain containing	0.557
TMEM182	NXPH1	ENSP00000394178	ENSP00000384551	Transmembrane protein 182	Neurexophilin-1; May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors	0.512
TMEM182	SMIM23	ENSP00000394178	ENSP00000331214	Transmembrane protein 182	Small integral membrane protein 23	0.531
TMEM182	TM6SF1	ENSP00000394178	ENSP00000317000	Transmembrane protein 182	Transmembrane 6 superfamily member 1; May function as sterol isomerase; Belongs to the TM6SF family	0.748

page 1 of 2

Network

Cooccurrence

Textmining

Coexpression

Experiments

Neighborhood

Databases

Fusion

© STRING Consortium 2020

Credits

Access

Info

About