ZNF7 protein (human) - STRING database

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ZNF7

Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (697 aa)

Predicted Functional Partners:

RPL8

0.885

RPS7

0.685

NOX4

0.649

TAF2

0.478

FCF1

0.473

GZMM

0.467

OSGIN2

0.452

NFXL1

0.445

ENSG00000228049

0.436

POLE4

0.434

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSG00000228049	OSGIN2	ENSP00000351218	ENSP00000396445	DNA-directed RNA polymerase II subunit RPB11-b1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity)	Oxidative stress-induced growth inhibitor 2; May be involved in meiosis or the maturation of germ cells	0.486
ENSG00000228049	ZNF7	ENSP00000351218	ENSP00000393260	DNA-directed RNA polymerase II subunit RPB11-b1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity)	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.436
FCF1	RPS7	ENSP00000344393	ENSP00000339095	rRNA-processing protein FCF1 homolog; Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly	40S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family	0.978
FCF1	ZNF7	ENSP00000344393	ENSP00000393260	rRNA-processing protein FCF1 homolog; Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.473
GZMM	ZNF7	ENSP00000264553	ENSP00000393260	Granzyme M; Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha- tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.467
NFXL1	ZNF7	ENSP00000422037	ENSP00000393260	NF-X1-type zinc finger protein NFXL1; Nuclear transcription factor, X-box binding like 1; Belongs to the NFX1 family	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.445
NOX4	ZNF7	ENSP00000263317	ENSP00000393260	NADPH oxidase 4; Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and is [...]	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.649
OSGIN2	ENSG00000228049	ENSP00000396445	ENSP00000351218	Oxidative stress-induced growth inhibitor 2; May be involved in meiosis or the maturation of germ cells	DNA-directed RNA polymerase II subunit RPB11-b1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity)	0.486
OSGIN2	ZNF7	ENSP00000396445	ENSP00000393260	Oxidative stress-induced growth inhibitor 2; May be involved in meiosis or the maturation of germ cells	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.452
POLE4	ZNF7	ENSP00000420176	ENSP00000393260	DNA polymerase epsilon subunit 4; May play a role in allowing polymerase epsilon to carry out its replication and/or repair function; DNA polymerases	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.434
RPL8	RPS7	ENSP00000262584	ENSP00000339095	60S ribosomal protein L8; Component of the large ribosomal subunit	40S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family	0.999
RPL8	ZNF7	ENSP00000262584	ENSP00000393260	60S ribosomal protein L8; Component of the large ribosomal subunit	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.885
RPS7	FCF1	ENSP00000339095	ENSP00000344393	40S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family	rRNA-processing protein FCF1 homolog; Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly	0.978
RPS7	RPL8	ENSP00000339095	ENSP00000262584	40S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family	60S ribosomal protein L8; Component of the large ribosomal subunit	0.999
RPS7	ZNF7	ENSP00000339095	ENSP00000393260	40S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.685
TAF2	ZNF7	ENSP00000367406	ENSP00000393260	Transcription initiation factor TFIID subunit 2; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.478
ZNF7	ENSG00000228049	ENSP00000393260	ENSP00000351218	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	DNA-directed RNA polymerase II subunit RPB11-b1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity)	0.436
ZNF7	FCF1	ENSP00000393260	ENSP00000344393	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	rRNA-processing protein FCF1 homolog; Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly	0.473
ZNF7	GZMM	ENSP00000393260	ENSP00000264553	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Granzyme M; Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha- tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells	0.467
ZNF7	NFXL1	ENSP00000393260	ENSP00000422037	Zinc finger protein 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	NF-X1-type zinc finger protein NFXL1; Nuclear transcription factor, X-box binding like 1; Belongs to the NFX1 family	0.445

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