AGAP4 protein (human) - STRING database

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AGAP4

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing (663 aa)

Predicted Functional Partners:

C2orf43

0.587

ANKRD31

0.532

ZNF620

0.514

GRAMD1A

0.510

HDHD3

0.477

AHDC1

0.473

CXorf36

0.453

ZPLD1

0.446

RFX6

0.444

PLEKHS1

0.422

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGAP4	AHDC1	ENSP00000392513	ENSP00000363123	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	AT-hook DNA-binding motif-containing protein 1; AT-hook DNA binding motif containing 1	0.473
AGAP4	ANKRD31	ENSP00000392513	ENSP00000274361	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	Putative ankyrin repeat domain-containing protein 31; Ankyrin repeat domain containing	0.532
AGAP4	C2orf43	ENSP00000392513	ENSP00000237822	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	Lipid droplet-associated hydrolase; Serine lipid hydrolase associated with lipid droplets. Highly expressed in macrophage-rich areas in atherosclerotic lesions, suggesting that it could promote cholesterol ester turnover in macrophages; Belongs to the AB hydrolase superfamily. LDAH family	0.587
AGAP4	CXorf36	ENSP00000392513	ENSP00000381086	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	Deleted in autism-related protein 1; Chromosome X open reading frame 36	0.453
AGAP4	GRAMD1A	ENSP00000392513	ENSP00000441032	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	GRAM domain-containing protein 1A; May play a role in tumor progression; GRAM domain containing	0.510
AGAP4	HDHD3	ENSP00000392513	ENSP00000238379	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	Haloacid dehalogenase like hydrolase domain containing 3	0.477
AGAP4	PLEKHS1	ENSP00000392513	ENSP00000358316	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	Pleckstrin homology domain containing S1	0.422
AGAP4	RFX6	ENSP00000392513	ENSP00000332208	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	DNA-binding protein RFX6; Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin. Not required for pancreatic PP (polypeptide- producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by [...]	0.444
AGAP4	ZNF620	ENSP00000392513	ENSP00000322265	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	Zinc finger protein 620; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.514
AGAP4	ZPLD1	ENSP00000392513	ENSP00000307801	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	Zona pellucida-like domain-containing protein 1; Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ	0.446
AHDC1	AGAP4	ENSP00000363123	ENSP00000392513	AT-hook DNA-binding motif-containing protein 1; AT-hook DNA binding motif containing 1	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	0.473
ANKRD31	AGAP4	ENSP00000274361	ENSP00000392513	Putative ankyrin repeat domain-containing protein 31; Ankyrin repeat domain containing	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	0.532
ANKRD31	GRAMD1A	ENSP00000274361	ENSP00000441032	Putative ankyrin repeat domain-containing protein 31; Ankyrin repeat domain containing	GRAM domain-containing protein 1A; May play a role in tumor progression; GRAM domain containing	0.559
ANKRD31	ZNF620	ENSP00000274361	ENSP00000322265	Putative ankyrin repeat domain-containing protein 31; Ankyrin repeat domain containing	Zinc finger protein 620; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.575
C2orf43	AGAP4	ENSP00000237822	ENSP00000392513	Lipid droplet-associated hydrolase; Serine lipid hydrolase associated with lipid droplets. Highly expressed in macrophage-rich areas in atherosclerotic lesions, suggesting that it could promote cholesterol ester turnover in macrophages; Belongs to the AB hydrolase superfamily. LDAH family	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	0.587
C2orf43	RFX6	ENSP00000237822	ENSP00000332208	Lipid droplet-associated hydrolase; Serine lipid hydrolase associated with lipid droplets. Highly expressed in macrophage-rich areas in atherosclerotic lesions, suggesting that it could promote cholesterol ester turnover in macrophages; Belongs to the AB hydrolase superfamily. LDAH family	DNA-binding protein RFX6; Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin. Not required for pancreatic PP (polypeptide- producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by [...]	0.601
CXorf36	AGAP4	ENSP00000381086	ENSP00000392513	Deleted in autism-related protein 1; Chromosome X open reading frame 36	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	0.453
GRAMD1A	AGAP4	ENSP00000441032	ENSP00000392513	GRAM domain-containing protein 1A; May play a role in tumor progression; GRAM domain containing	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; Putative GTPase-activating protein; Ankyrin repeat domain containing	0.510
GRAMD1A	ANKRD31	ENSP00000441032	ENSP00000274361	GRAM domain-containing protein 1A; May play a role in tumor progression; GRAM domain containing	Putative ankyrin repeat domain-containing protein 31; Ankyrin repeat domain containing	0.559
GRAMD1A	ZNF620	ENSP00000441032	ENSP00000322265	GRAM domain-containing protein 1A; May play a role in tumor progression; GRAM domain containing	Zinc finger protein 620; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.565

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