C14orf105 protein (human) - STRING database

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C14orf105

Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105 (336 aa)

Predicted Functional Partners:

C14orf37

0.658

ZNF705A

0.646

SLC35F4

0.589

TM4SF4

0.569

KIF12

0.567

FBXO27

0.530

ZDHHC11

0.514

SGK2

0.496

CATSPER2

0.473

AP5M1

0.473

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP5M1	C14orf105	ENSP00000261558	ENSP00000392368	AP-5 complex subunit mu-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed-18395520, it may play a role in cell death; Belongs to the adaptor complexes medium subunit family	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	0.473
AP5M1	C14orf37	ENSP00000261558	ENSP00000267485	AP-5 complex subunit mu-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed-18395520, it may play a role in cell death; Belongs to the adaptor complexes medium subunit family	Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37	0.473
AP5M1	SLC35F4	ENSP00000261558	ENSP00000342518	AP-5 complex subunit mu-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed-18395520, it may play a role in cell death; Belongs to the adaptor complexes medium subunit family	Solute carrier family 35 member F4; Putative solute transporter	0.454
C14orf105	AP5M1	ENSP00000392368	ENSP00000261558	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	AP-5 complex subunit mu-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed-18395520, it may play a role in cell death; Belongs to the adaptor complexes medium subunit family	0.473
C14orf105	C14orf37	ENSP00000392368	ENSP00000267485	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37	0.658
C14orf105	CATSPER2	ENSP00000392368	ENSP00000371180	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	Cation channel sperm-associated protein 2; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte; Belongs to the cation channel sperm-associated (TC 1.A.1.19) family	0.473
C14orf105	FBXO27	ENSP00000392368	ENSP00000292853	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	F-box only protein 27; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex- type oligosaccharides; F-boxes other	0.530
C14orf105	KIF12	ENSP00000392368	ENSP00000363232	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	Kinesin-like protein KIF12; Kinesin family member 12; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family	0.567
C14orf105	SGK2	ENSP00000392368	ENSP00000340608	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	Serine/threonine-protein kinase Sgk2; Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels- SCNN1A/ENAC, K(+) channels- KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter- SLC6A19, glutamate transporter- SLC1A6/EAAT4, glutamate receptors- GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger- SLC9A3/NHE3, and the Na(+)/K(+) ATPase	0.496
C14orf105	SLC35F4	ENSP00000392368	ENSP00000342518	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	Solute carrier family 35 member F4; Putative solute transporter	0.589
C14orf105	TM4SF4	ENSP00000392368	ENSP00000305852	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	Transmembrane 4 L6 family member 4; Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation	0.569
C14orf105	ZDHHC11	ENSP00000392368	ENSP00000283441	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	Probable palmitoyltransferase ZDHHC11; Zinc finger DHHC-type containing 11; Belongs to the DHHC palmitoyltransferase family	0.514
C14orf105	ZNF705A	ENSP00000392368	ENSP00000352233	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	Zinc finger protein 705A; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.646
C14orf37	AP5M1	ENSP00000267485	ENSP00000261558	Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37	AP-5 complex subunit mu-1; As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed-18395520, it may play a role in cell death; Belongs to the adaptor complexes medium subunit family	0.473
C14orf37	C14orf105	ENSP00000267485	ENSP00000392368	Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	0.658
C14orf37	SLC35F4	ENSP00000267485	ENSP00000342518	Uncharacterized protein C14orf37; Chromosome 14 open reading frame 37	Solute carrier family 35 member F4; Putative solute transporter	0.615
CATSPER2	C14orf105	ENSP00000371180	ENSP00000392368	Cation channel sperm-associated protein 2; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte; Belongs to the cation channel sperm-associated (TC 1.A.1.19) family	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	0.473
FBXO27	C14orf105	ENSP00000292853	ENSP00000392368	F-box only protein 27; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex- type oligosaccharides; F-boxes other	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	0.530
KIF12	C14orf105	ENSP00000363232	ENSP00000392368	Kinesin-like protein KIF12; Kinesin family member 12; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	0.567
SGK2	C14orf105	ENSP00000340608	ENSP00000392368	Serine/threonine-protein kinase Sgk2; Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels- SCNN1A/ENAC, K(+) channels- KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter- SLC6A19, glutamate transporter- SLC1A6/EAAT4, glutamate receptors- GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger- SLC9A3/NHE3, and the Na(+)/K(+) ATPase	Uncharacterized protein CCDC198; Chromosome 14 open reading frame 105	0.496

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