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  • 11.0 [archived version]
STRINGSTRING
PRSS56 PRSS56 WNT8B WNT8B VSX2 VSX2 WNT8A WNT8A ENSG00000235718 ENSG00000235718 WNT9B WNT9B WNT10A WNT10A NR2E3 NR2E3 WNT5B WNT5B PRPH2 PRPH2 RD3 RD3
"ENSG00000235718" - Membrane frizzled-related protein in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ENSG00000235718Membrane frizzled-related protein; May play a role in eye development (579 aa)    
Predicted Functional Partners:
PRSS56
Serine protease 56; Serine protease required during eye development (603 aa)
           
  0.796
RD3
Protein RD3; Retinal degeneration 3 (195 aa)
           
  0.714
PRPH2
Peripherin-2; May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis; Belongs to the PRPH2/ROM1 family (346 aa)
           
  0.671
WNT8A
Protein Wnt-8a; Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus (369 aa)
     
 
  0.659
VSX2
Visual system homeobox 2; Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells (By similarity); Belongs to the paired homeobox family (361 aa)
     
   
  0.658
WNT8B
Protein Wnt-8b; Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus (351 aa)
     
 
  0.655
WNT9B
Protein Wnt-9b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity) (357 aa)
     
 
  0.655
WNT5B
Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family (359 aa)
     
 
  0.646
WNT10A
Protein Wnt-10a; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters; Belongs to the Wnt family (417 aa)
     
 
  0.646
NR2E3
Photoreceptor-specific nuclear receptor; Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression; Nuclear hormone receptors (410 aa)
     
 
  0.644
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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