• Version:
  • 11.0 [archived version]
STRINGSTRING
LY6E LY6E EIF2B2 EIF2B2 SLC5A4 SLC5A4 CCDC173 CCDC173 FNDC1 FNDC1 CARF CARF AGPS AGPS C1orf27 C1orf27 PDILT PDILT MYO1B MYO1B
"CCDC173" - Coiled-coil domain containing 173 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
CCDC173Coiled-coil domain containing 173 (552 aa)    
Predicted Functional Partners:
C1orf27
Protein odr-4 homolog; May play a role in the trafficking of a subset of G- protein coupled receptors; Belongs to the ODR-4 family (454 aa)
           
  0.828
CARF
Calcium-responsive transcription factor; Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5’-CTATTTCGAG-3’ sequence (725 aa)
           
  0.775
EIF2B2
Translation initiation factor eIF-2B subunit beta; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family (351 aa)
           
  0.704
FNDC1
Fibronectin type III domain-containing protein 1; May be an activator of G protein signaling; Fibronectin type III domain containing (1894 aa)
           
  0.572
AGPS
Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family (658 aa)
           
  0.532
PDILT
Protein disulfide-isomerase-like protein of the testis; Probable redox-inactive chaperone involved in spermatogenesis; Belongs to the protein disulfide isomerase family (584 aa)
     
   
  0.484
LY6E
Lymphocyte antigen 6E; Involved in T-cell development. Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3-beta-4-containing nAChRs maximum response; LY6/PLAUR domain containing (131 aa)
           
  0.471
MYO1B
Unconventional myosin-Ib; Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport; Myosins, class I (1136 aa)
           
  0.469
SLC5A4
Solute carrier family 5 member 4; Has electrogenic activity in response to glucose, and may function as a glucose sensor. Mediates influx of sodium ions into the cell but does not transport sugars. Also potently activated by imino sugars such as deoxynojirimycin (DNJ); Belongs to the sodium-solute symporter (SSF) (TC 2.A.21) family (659 aa)
           
  0.463
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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