node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FITM2 | GCC1 | ENSP00000380037 | ENSP00000318821 | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | 0.642 |
FITM2 | KCNK16 | ENSP00000380037 | ENSP00000391498 | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | 0.649 |
FITM2 | PSMD6 | ENSP00000380037 | ENSP00000418695 | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | Proteasome 26S subunit, non-ATPase 6 | 0.570 |
FITM2 | R3HDML | ENSP00000380037 | ENSP00000217043 | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | Peptidase inhibitor R3HDML; Putative serine protease inhibitor; CAP superfamily | 0.703 |
FITM2 | ZFAND3 | ENSP00000380037 | ENSP00000287218 | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | Zinc finger AN1-type containing 3 | 0.669 |
GCC1 | FITM2 | ENSP00000318821 | ENSP00000380037 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | 0.642 |
GCC1 | KCNK16 | ENSP00000318821 | ENSP00000391498 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | 0.669 |
GCC1 | PSMD6 | ENSP00000318821 | ENSP00000418695 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | Proteasome 26S subunit, non-ATPase 6 | 0.643 |
GCC1 | R3HDML | ENSP00000318821 | ENSP00000217043 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | Peptidase inhibitor R3HDML; Putative serine protease inhibitor; CAP superfamily | 0.672 |
GCC1 | ZFAND3 | ENSP00000318821 | ENSP00000287218 | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | Zinc finger AN1-type containing 3 | 0.669 |
INS | KCNK16 | ENSP00000380432 | ENSP00000391498 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | 0.680 |
KCNK16 | FITM2 | ENSP00000391498 | ENSP00000380037 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization | 0.649 |
KCNK16 | GCC1 | ENSP00000391498 | ENSP00000318821 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | GRIP and coiled-coil domain-containing protein 1; Probably involved in maintaining Golgi structure | 0.669 |
KCNK16 | INS | ENSP00000391498 | ENSP00000380432 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver | 0.680 |
KCNK16 | KCNRG | ENSP00000391498 | ENSP00000324191 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes | 0.612 |
KCNK16 | KCTD18 | ENSP00000391498 | ENSP00000352941 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | BTB/POZ domain-containing protein KCTD18; Potassium channel tetramerization domain containing 18 | 0.598 |
KCNK16 | PSMD6 | ENSP00000391498 | ENSP00000418695 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Proteasome 26S subunit, non-ATPase 6 | 0.585 |
KCNK16 | R3HDML | ENSP00000391498 | ENSP00000217043 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Peptidase inhibitor R3HDML; Putative serine protease inhibitor; CAP superfamily | 0.673 |
KCNK16 | RIN2 | ENSP00000391498 | ENSP00000255006 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Ras and Rab interactor 2; Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP; Belongs to the RIN (Ras interaction/interference) family | 0.590 |
KCNK16 | SLC24A3 | ENSP00000391498 | ENSP00000333519 | Potassium channel subfamily K member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents; Potassium two pore domain channel subfamily K | Sodium/potassium/calcium exchanger 3; Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+); Solute carriers | 0.589 |