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STRINGSTRING
LIMS3L LIMS3L ALS2CR11 ALS2CR11 KIAA1751 KIAA1751 TSACC TSACC SLC25A51 SLC25A51 RIMBP3C RIMBP3C C22orf23 C22orf23 RIMBP3B RIMBP3B RIMBP3 RIMBP3 MAPK8IP2 MAPK8IP2 MAPK8IP1 MAPK8IP1
"RIMBP3C" - RIMS binding protein 3C in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
RIMBP3CRIMS binding protein 3C; Belongs to the RIMBP family (1639 aa)    
Predicted Functional Partners:
RIMBP3
RIMS-binding protein 3A; Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Important for male fertility; Belongs to the RIMBP family (1639 aa)
      
 
0.807
RIMBP3B
RIMS binding protein 3B (1639 aa)
        
 
0.801
TSACC
TSSK6-activating co-chaperone protein; Co-chaperone that facilitates HSP-mediated activation of TSSK6; Belongs to the TSACC family (125 aa)
            
  0.647
MAPK8IP2
C-Jun-amino-terminal kinase-interacting protein 2; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity) (824 aa)
      
 
  0.589
MAPK8IP1
C-Jun-amino-terminal kinase-interacting protein 1; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. Cytoplasmic MAPK8IP1 causes inhibition of JNK- regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun. May also participate in ApoER2-specific reelin signaling. Directly, or indirectly, regulates GLUT2 gene expression and beta-cell function. [...] (711 aa)
      
 
  0.589
ALS2CR11
C2 calcium-dependent domain-containing protein 6; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 (1820 aa)
            
  0.577
SLC25A51
Solute carrier family 25 member 51 (297 aa)
            
  0.558
C22orf23
UPF0193 protein EVG1; Chromosome 22 open reading frame 23 (217 aa)
            
  0.557
KIAA1751
Cilia- and flagella-associated protein 74; As part of the central apparatus of the cilium axoneme may play a role in cilium movement (1584 aa)
            
  0.554
LIMS3L
LIM and senescent cell antigen-like domains 3-like (117 aa)
            
  0.554
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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