• Version:
  • 11.0 [archived version]
STRINGSTRING
GPR88 GPR88 GPR139 GPR139 GPR111 GPR111 GPR148 GPR148 STXBP3 STXBP3 PPRC1 PPRC1 GPR141 GPR141 GPR110 GPR110 GPR135 GPR135 RHO RHO GPR142 GPR142
"GPR141" - Probable G-protein coupled receptor 141 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR141Probable G-protein coupled receptor 141; Orphan receptor; G protein-coupled receptors, Class A orphans (305 aa)    
Predicted Functional Partners:
GPR142
Probable G-protein coupled receptor 142; Orphan receptor; G protein-coupled receptors, Class A orphans (462 aa)
           
  0.826
GPR148
Probable G-protein coupled receptor 148; Orphan receptor; G protein-coupled receptors, Class A orphans (347 aa)
           
  0.774
GPR139
Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway; G protein-coupled receptors, Class A orphans (353 aa)
           
  0.759
GPR111
Adhesion G-protein coupled receptor F2; Orphan receptor (708 aa)
           
  0.726
GPR110
Adhesion G-protein coupled receptor F1; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily (910 aa)
           
  0.721
GPR135
Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans (494 aa)
           
  0.668
STXBP3
Syntaxin-binding protein 3; Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (592 aa)
       
      0.666
RHO
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily (348 aa)
           
  0.641
GPR88
Probable G-protein coupled receptor 88; Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function (384 aa)
           
  0.603
PPRC1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1; Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes; RNA binding motif containing (1664 aa)
           
  0.585
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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