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  • 11.0 [archived version]
STRINGSTRING
UNC5A UNC5A FNDC3A FNDC3A FAM131A FAM131A FAM134C FAM134C YIF1B YIF1B DPY19L4 DPY19L4 YIF1A YIF1A FAM134A FAM134A FBXL6 FBXL6 FAM114A1 FAM114A1 C8orf37 C8orf37
"DPY19L4" - Probable C-mannosyltransferase DPY19L4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DPY19L4Probable C-mannosyltransferase DPY19L4; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (723 aa)    
Predicted Functional Partners:
FAM134C
Reticulophagy regulator 3; Mediates NRF1-enhanced neurite outgrowth; Belongs to the RETREG family (466 aa)
            
  0.718
FAM134A
Reticulophagy regulator 2; Family with sequence similarity 134, member A; Belongs to the RETREG family (543 aa)
            
  0.683
FAM114A1
Protein NOXP20; May play a role in neuronal cell development; Belongs to the FAM114 family (563 aa)
            
  0.582
YIF1B
Protein YIF1B; Yip1 interacting factor homolog B, membrane trafficking protein; Belongs to the YIF1 family (314 aa)
            
  0.575
FAM131A
Protein FAM131A; Family with sequence similarity 131 member A; Belongs to the FAM131 family (366 aa)
            
  0.570
C8orf37
Protein C8orf37; Chromosome 8 open reading frame 37; Bardet-Biedl syndrome associated (207 aa)
      
   
  0.568
UNC5A
Netrin receptor UNC5A; Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin. Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand; I-set domain containing (842 aa)
            
  0.565
YIF1A
Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the YIF1 family (293 aa)
            
  0.558
FNDC3A
Fibronectin type-III domain-containing protein 3A; Mediates spermatid-Sertoli adhesion during spermatogenesis; Belongs to the FNDC3 family (1198 aa)
      
   
  0.522
FBXL6
F-box/LRR-repeat protein 6; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins (539 aa)
      
   
  0.516
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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