node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADPGK | GLYCTK | ENSP00000312250 | ENSP00000389175 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity) | Glycerate kinase; Belongs to the glycerate kinase type-2 family | 0.905 |
ADPGK | TPI1 | ENSP00000312250 | ENSP00000229270 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity) | Triosephosphate isomerase 1; Belongs to the triosephosphate isomerase family | 0.457 |
ALDH1B1 | ALDH2 | ENSP00000366927 | ENSP00000261733 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation | Aldehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase 2 family member; Belongs to the aldehyde dehydrogenase family | 0.809 |
ALDH1B1 | ALDH3A2 | ENSP00000366927 | ENSP00000345774 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation | Fatty aldehyde dehydrogenase; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid | 0.858 |
ALDH1B1 | GLYCTK | ENSP00000366927 | ENSP00000389175 | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation | Glycerate kinase; Belongs to the glycerate kinase type-2 family | 0.922 |
ALDH2 | ALDH1B1 | ENSP00000261733 | ENSP00000366927 | Aldehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase 2 family member; Belongs to the aldehyde dehydrogenase family | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation | 0.809 |
ALDH2 | ALDH3A2 | ENSP00000261733 | ENSP00000345774 | Aldehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase 2 family member; Belongs to the aldehyde dehydrogenase family | Fatty aldehyde dehydrogenase; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid | 0.858 |
ALDH2 | GLYCTK | ENSP00000261733 | ENSP00000389175 | Aldehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase 2 family member; Belongs to the aldehyde dehydrogenase family | Glycerate kinase; Belongs to the glycerate kinase type-2 family | 0.914 |
ALDH2 | TPI1 | ENSP00000261733 | ENSP00000229270 | Aldehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase 2 family member; Belongs to the aldehyde dehydrogenase family | Triosephosphate isomerase 1; Belongs to the triosephosphate isomerase family | 0.436 |
ALDH3A2 | ALDH1B1 | ENSP00000345774 | ENSP00000366927 | Fatty aldehyde dehydrogenase; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation | 0.858 |
ALDH3A2 | ALDH2 | ENSP00000345774 | ENSP00000261733 | Fatty aldehyde dehydrogenase; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid | Aldehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase 2 family member; Belongs to the aldehyde dehydrogenase family | 0.858 |
ALDH3A2 | GLYCTK | ENSP00000345774 | ENSP00000389175 | Fatty aldehyde dehydrogenase; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid | Glycerate kinase; Belongs to the glycerate kinase type-2 family | 0.919 |
ALDH3A2 | TPI1 | ENSP00000345774 | ENSP00000229270 | Fatty aldehyde dehydrogenase; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid | Triosephosphate isomerase 1; Belongs to the triosephosphate isomerase family | 0.494 |
ALDH7A1 | GLYCTK | ENSP00000387123 | ENSP00000389175 | Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism | Glycerate kinase; Belongs to the glycerate kinase type-2 family | 0.915 |
ALDH9A1 | GLYCTK | ENSP00000346827 | ENSP00000389175 | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction | Glycerate kinase; Belongs to the glycerate kinase type-2 family | 0.931 |
GLYCTK | ADPGK | ENSP00000389175 | ENSP00000312250 | Glycerate kinase; Belongs to the glycerate kinase type-2 family | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity) | 0.905 |
GLYCTK | ALDH1B1 | ENSP00000389175 | ENSP00000366927 | Glycerate kinase; Belongs to the glycerate kinase type-2 family | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation | 0.922 |
GLYCTK | ALDH2 | ENSP00000389175 | ENSP00000261733 | Glycerate kinase; Belongs to the glycerate kinase type-2 family | Aldehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase 2 family member; Belongs to the aldehyde dehydrogenase family | 0.914 |
GLYCTK | ALDH3A2 | ENSP00000389175 | ENSP00000345774 | Glycerate kinase; Belongs to the glycerate kinase type-2 family | Fatty aldehyde dehydrogenase; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid | 0.919 |
GLYCTK | ALDH7A1 | ENSP00000389175 | ENSP00000387123 | Glycerate kinase; Belongs to the glycerate kinase type-2 family | Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism | 0.915 |