• Version:
  • 11.0 [archived version]
STRINGSTRING
ALDH9A1 ALDH9A1 ALDH7A1 ALDH7A1 ALDH1B1 ALDH1B1 ALDH3A2 ALDH3A2 GLYCTK GLYCTK ADPGK ADPGK ALDH2 ALDH2 TPI1 TPI1 GRHPR GRHPR PGAM4 PGAM4 PGAM1 PGAM1
"GLYCTK" - Glycerate kinase in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
GLYCTKGlycerate kinase; Belongs to the glycerate kinase type-2 family (523 aa)    
Predicted Functional Partners:
GRHPR
Glyoxylate reductase/hydroxypyruvate reductase; Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate (328 aa)
 
 
  0.978
ALDH9A1
4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction (518 aa)
     
 
  0.931
ALDH1B1
Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (517 aa)
     
 
  0.922
ALDH3A2
Fatty aldehyde dehydrogenase; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid (508 aa)
     
 
  0.919
TPI1
Triosephosphate isomerase 1; Belongs to the triosephosphate isomerase family (286 aa)
         
  0.915
ALDH7A1
Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (539 aa)
     
 
  0.915
ALDH2
Aldehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase 2 family member; Belongs to the aldehyde dehydrogenase family (517 aa)
     
 
  0.914
PGAM4
Phosphoglycerate mutase family member 4; Bisphosphoglycerate phosphatases (254 aa)
         
  0.910
PGAM1
Phosphoglycerate mutase 1; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity (254 aa)
         
  0.907
ADPGK
ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity) (496 aa)
         
  0.905
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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