RWDD4 protein (human) - STRING database

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RWDD4

RWD domain containing 4 (188 aa)

Predicted Functional Partners:

DRG2

0.874

DRG1

0.699

ZNF330

0.692

RWDD1

0.682

EBNA1BP2

0.627

RWDD2A

0.588

ZC3H15

0.542

ASB15

0.539

KRI1

0.539

CENPU

0.506

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB15	RWDD4	ENSP00000397655	ENSP00000388920	Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family	RWD domain containing 4	0.539
CENPU	RWDD4	ENSP00000281453	ENSP00000388920	Centromere protein U; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in tra [...]	RWD domain containing 4	0.506
DRG1	DRG2	ENSP00000329715	ENSP00000225729	Developmentally-regulated GTP-binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	Developmentally-regulated GTP-binding protein 2; May play a role in cell proliferation, differentiation and death; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family	0.521
DRG1	RWDD1	ENSP00000329715	ENSP00000420357	Developmentally-regulated GTP-binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	RWD domain-containing protein 1; Protects DRG2 from proteolytic degradation; Belongs to the RWDD1/GIR2 family	0.928
DRG1	RWDD2A	ENSP00000329715	ENSP00000358739	Developmentally-regulated GTP-binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	RWD domain containing 2A	0.442
DRG1	RWDD4	ENSP00000329715	ENSP00000388920	Developmentally-regulated GTP-binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	RWD domain containing 4	0.699
DRG1	ZC3H15	ENSP00000329715	ENSP00000338788	Developmentally-regulated GTP-binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	Zinc finger CCCH domain-containing protein 15; Protects DRG1 from proteolytic degradation; Zinc fingers CCCH-type	0.997
DRG2	DRG1	ENSP00000225729	ENSP00000329715	Developmentally-regulated GTP-binding protein 2; May play a role in cell proliferation, differentiation and death; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family	Developmentally-regulated GTP-binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	0.521
DRG2	RWDD1	ENSP00000225729	ENSP00000420357	Developmentally-regulated GTP-binding protein 2; May play a role in cell proliferation, differentiation and death; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family	RWD domain-containing protein 1; Protects DRG2 from proteolytic degradation; Belongs to the RWDD1/GIR2 family	0.992
DRG2	RWDD4	ENSP00000225729	ENSP00000388920	Developmentally-regulated GTP-binding protein 2; May play a role in cell proliferation, differentiation and death; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family	RWD domain containing 4	0.874
DRG2	ZC3H15	ENSP00000225729	ENSP00000338788	Developmentally-regulated GTP-binding protein 2; May play a role in cell proliferation, differentiation and death; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family	Zinc finger CCCH domain-containing protein 15; Protects DRG1 from proteolytic degradation; Zinc fingers CCCH-type	0.959
EBNA1BP2	KRI1	ENSP00000407323	ENSP00000320917	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA; Belongs to the EBP2 family	KRI1 homolog; Belongs to the KRI1 family	0.899
EBNA1BP2	RWDD1	ENSP00000407323	ENSP00000420357	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA; Belongs to the EBP2 family	RWD domain-containing protein 1; Protects DRG2 from proteolytic degradation; Belongs to the RWDD1/GIR2 family	0.666
EBNA1BP2	RWDD4	ENSP00000407323	ENSP00000388920	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA; Belongs to the EBP2 family	RWD domain containing 4	0.627
EBNA1BP2	ZC3H15	ENSP00000407323	ENSP00000338788	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA; Belongs to the EBP2 family	Zinc finger CCCH domain-containing protein 15; Protects DRG1 from proteolytic degradation; Zinc fingers CCCH-type	0.598
KRI1	EBNA1BP2	ENSP00000320917	ENSP00000407323	KRI1 homolog; Belongs to the KRI1 family	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA; Belongs to the EBP2 family	0.899
KRI1	RWDD1	ENSP00000320917	ENSP00000420357	KRI1 homolog; Belongs to the KRI1 family	RWD domain-containing protein 1; Protects DRG2 from proteolytic degradation; Belongs to the RWDD1/GIR2 family	0.652
KRI1	RWDD4	ENSP00000320917	ENSP00000388920	KRI1 homolog; Belongs to the KRI1 family	RWD domain containing 4	0.539
RWDD1	DRG1	ENSP00000420357	ENSP00000329715	RWD domain-containing protein 1; Protects DRG2 from proteolytic degradation; Belongs to the RWDD1/GIR2 family	Developmentally-regulated GTP-binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	0.928
RWDD1	DRG2	ENSP00000420357	ENSP00000225729	RWD domain-containing protein 1; Protects DRG2 from proteolytic degradation; Belongs to the RWDD1/GIR2 family	Developmentally-regulated GTP-binding protein 2; May play a role in cell proliferation, differentiation and death; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family	0.992

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