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  • 11.0 [archived version]
STRINGSTRING
TMEM41A TMEM41A TMEM199 TMEM199 TMEM126A TMEM126A POPDC2 POPDC2 C17orf62 C17orf62 ANKMY1 ANKMY1 TMEM209 TMEM209 TMEM201 TMEM201 DHRS7 DHRS7 TMEM38A TMEM38A TMTC3 TMTC3
"C17orf62" - Uncharacterized protein C17orf62 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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C17orf62Uncharacterized protein C17orf62; Chromosome 17 open reading frame 62 (187 aa)    
Predicted Functional Partners:
TMEM126A
Transmembrane protein 126A; Belongs to the TMEM126 family (195 aa)
           
  0.765
TMEM199
Transmembrane protein 199; Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis (208 aa)
           
  0.730
DHRS7
Dehydrogenase/reductase SDR family member 7; Short chain dehydrogenase/reductase superfamily (339 aa)
           
  0.716
TMEM41A
Transmembrane protein 41A; Belongs to the TMEM41 family (264 aa)
           
  0.715
TMEM38A
Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (299 aa)
           
  0.709
ANKMY1
Ankyrin repeat and MYND domain containing 1 (1030 aa)
           
  0.692
TMEM209
Transmembrane protein 209 (561 aa)
           
  0.668
TMTC3
Transmembrane and TPR repeat-containing protein 3; Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response; Tetratricopeptide repeat domain containing (914 aa)
           
  0.621
TMEM201
Transmembrane protein 201; Involved in nuclear movement during fibroblast polarization and migration. Proposed to be involved in actin- dependent nuclear movement via association with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow (By similarity). Overexpression can recruit Ran GTPase to the nuclear periphery (666 aa)
           
  0.555
POPDC2
Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density; Belongs to the popeye family (364 aa)
           
  0.536
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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