• Version:
  • 11.0 [archived version]
STRINGSTRING
PRDM7 PRDM7 OR2A2 OR2A2 C11orf94 C11orf94 TRIM28 TRIM28 ZDHHC12 ZDHHC12 ZNF419 ZNF419 MYPOP MYPOP KIAA1551 KIAA1551 HMSD HMSD ZZZ3 ZZZ3 ZNF608 ZNF608
"ZNF419" - Zinc finger protein 419 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF419Zinc finger protein 419; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (511 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.903
HMSD
Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens (139 aa)
       
 
  0.654
C11orf94
Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94 (98 aa)
           
  0.628
OR2A2
Olfactory receptor 2A2; Odorant receptor; Olfactory receptors, family 2 (318 aa)
           
  0.553
PRDM7
Probable histone-lysine N-methyltransferase PRDM7; Probable histone methyltransferase; PR/SET domain family (492 aa)
       
 
  0.540
ZZZ3
ZZ-type zinc finger-containing protein 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (903 aa)
           
  0.536
MYPOP
Myb-related transcription factor, partner of profilin; Transcriptional repressor; DNA-binding protein that specifically recognizes the core sequence 5’-YAAC[GT]G-3’. Dimerization with PFN1 reduces its DNA-binding capacity (By similarity); Myb/SANT domain containing (399 aa)
           
  0.520
ZNF608
Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription; Zinc fingers C2H2-type (1512 aa)
           
  0.482
ZDHHC12
Probable palmitoyltransferase ZDHHC12; Zinc finger DHHC-type containing 12; Belongs to the DHHC palmitoyltransferase family (267 aa)
       
 
  0.456
KIAA1551
Uncharacterized protein KIAA1551; Minor histocompatibility antigens (1747 aa)
           
  0.443
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]