• Version:
  • 11.0 [archived version]
STRINGSTRING
ZBTB8A ZBTB8A RGAG4 RGAG4 ZIK1 ZIK1 ZNF426 ZNF426 PEG10 PEG10 PNMA5 PNMA5 WFDC12 WFDC12 LDOC1 LDOC1 ZNF251 ZNF251 CDR2L CDR2L ZCCHC5 ZCCHC5
"PNMA5" - Paraneoplastic antigen-like protein 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNMA5Paraneoplastic antigen-like protein 5; Paraneoplastic Ma antigens; Belongs to the PNMA family (448 aa)    
Predicted Functional Partners:
ZCCHC5
Retrotransposon Gag-like protein 3; May function as a transcriptional regulator. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (475 aa)
           
  0.818
ZNF251
Zinc finger protein 251; May be involved in transcriptional regulation; Zinc fingers C2H2-type (671 aa)
           
  0.777
PEG10
Retrotransposon-derived protein PEG10; Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5’-GCCTGTCTTT-3’ DNA sequence of the MB1 domain in the myelin basic protein (M [...] (401 aa)
           
  0.658
LDOC1
Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family (146 aa)
           
  0.600
ZNF426
Zinc finger protein 426; May be involved in transcriptional regulation; Zinc fingers C2H2-type (554 aa)
           
  0.583
ZIK1
Zinc finger protein interacting with ribonucleoprotein K; May be a transcriptional repressor; Zinc fingers C2H2-type (487 aa)
           
  0.569
RGAG4
Retrotransposon Gag-like protein 5; Retrotransposon gag domain containing 4 (569 aa)
     
   
  0.553
ZBTB8A
Zinc finger and BTB domain-containing protein 8A; May be involved in transcriptional regulation; BTB domain containing (441 aa)
       
      0.540
WFDC12
WAP four-disulfide core domain protein 12; Antibacterial protein. Putative acid-stable proteinase inhibitor; WAP four-disulfide core domain containing (111 aa)
           
  0.537
CDR2L
Cerebellar degeneration related protein 2 like (465 aa)
           
  0.510
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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