• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF276 ZNF276 ANAPC16 ANAPC16 SNRPA1 SNRPA1 NPY5R NPY5R GPATCH11 GPATCH11 ZRSR2 ZRSR2 PHF11 PHF11 C4orf33 C4orf33 DRC1 DRC1 TTC27 TTC27 CRIPT CRIPT
"GPATCH11" - G-patch domain containing 11 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPATCH11G-patch domain containing 11 (285 aa)    
Predicted Functional Partners:
ZRSR2
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2; Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3’-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP- dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing (482 aa)
     
      0.724
C4orf33
UPF0462 protein C4orf33; Chromosome 4 open reading frame 33 (199 aa)
           
  0.702
TTC27
Tetratricopeptide repeat domain containing; Belongs to the TTC27 family (843 aa)
           
  0.673
DRC1
Dynein regulatory complex protein 1; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Required for the assembly and regulation of specific classes of inner dynein arm motors. May also function to restrict dynein-driven microtubule sliding, thus aiding in the generation of ciliary bending (740 aa)
           
  0.665
SNRPA1
U2 small nuclear ribonucleoprotein A; This protein is associated with sn-RNP U2. It helps the A’ protein to bind stem loop IV of U2 snRNA; Belongs to the U2 small nuclear ribonucleoprotein A family (255 aa)
       
      0.628
PHF11
PHD finger protein 11; Positive regulator of Th1-type cytokine gene expression; PHD finger proteins (331 aa)
     
   
  0.612
NPY5R
Neuropeptide Y receptor type 5; Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders (445 aa)
           
  0.611
ZNF276
Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type (614 aa)
           
  0.602
ANAPC16
Anaphase-promoting complex subunit 16; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins- it mainly mediates the formation of ’Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains; Belongs to the APC16 family (110 aa)
           
  0.589
CRIPT
Cysteine-rich PDZ-binding protein; Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses (101 aa)
           
  0.577
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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