MYADML2 protein (human) - STRING database

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MYADML2

Myeloid-associated differentiation marker-like protein 2; Myeloid associated differentiation marker like 2 (307 aa)

Predicted Functional Partners:

PAQR4

0.812

LMF1

0.777

COPS3

0.762

ADAP1

0.747

PCYT2

0.742

KCTD19

0.704

MAFG

0.664

STX1B

0.652

JAKMIP3

0.646

ARHGEF35

0.641

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAP1	COPS3	ENSP00000442682	ENSP00000268717	Arf-GAP with dual PH domain-containing protein 1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4); ArfGAPs	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-d [...]	0.692
ADAP1	LMF1	ENSP00000442682	ENSP00000262301	Arf-GAP with dual PH domain-containing protein 1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4); ArfGAPs	Lipase maturation factor 1; Involved in the maturation of specific proteins in the endoplasmic reticulum. Required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway. Each LMF1 molecule chaperones 50 or more molecules of LPL	0.703
ADAP1	MAFG	ENSP00000442682	ENSP00000350369	Arf-GAP with dual PH domain-containing protein 1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4); ArfGAPs	Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF- E2. Activates globin gene expression when associated with [...]	0.557
ADAP1	MYADML2	ENSP00000442682	ENSP00000386702	Arf-GAP with dual PH domain-containing protein 1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4); ArfGAPs	Myeloid-associated differentiation marker-like protein 2; Myeloid associated differentiation marker like 2	0.747
ADAP1	PCYT2	ENSP00000442682	ENSP00000442050	Arf-GAP with dual PH domain-containing protein 1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4); ArfGAPs	Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine	0.570
ARHGEF35	JAKMIP3	ENSP00000367355	ENSP00000298622	Rho guanine nucleotide exchange factor 35	Janus kinase and microtubule interacting protein 3	0.475
ARHGEF35	KCTD19	ENSP00000367355	ENSP00000305702	Rho guanine nucleotide exchange factor 35	BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19	0.500
ARHGEF35	MYADML2	ENSP00000367355	ENSP00000386702	Rho guanine nucleotide exchange factor 35	Myeloid-associated differentiation marker-like protein 2; Myeloid associated differentiation marker like 2	0.641
COPS3	ADAP1	ENSP00000268717	ENSP00000442682	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-d [...]	Arf-GAP with dual PH domain-containing protein 1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4); ArfGAPs	0.692
COPS3	LMF1	ENSP00000268717	ENSP00000262301	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-d [...]	Lipase maturation factor 1; Involved in the maturation of specific proteins in the endoplasmic reticulum. Required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway. Each LMF1 molecule chaperones 50 or more molecules of LPL	0.694
COPS3	MAFG	ENSP00000268717	ENSP00000350369	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-d [...]	Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF- E2. Activates globin gene expression when associated with [...]	0.547
COPS3	MYADML2	ENSP00000268717	ENSP00000386702	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-d [...]	Myeloid-associated differentiation marker-like protein 2; Myeloid associated differentiation marker like 2	0.762
COPS3	PCYT2	ENSP00000268717	ENSP00000442050	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-d [...]	Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine	0.622
JAKMIP3	ARHGEF35	ENSP00000298622	ENSP00000367355	Janus kinase and microtubule interacting protein 3	Rho guanine nucleotide exchange factor 35	0.475
JAKMIP3	KCTD19	ENSP00000298622	ENSP00000305702	Janus kinase and microtubule interacting protein 3	BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19	0.525
JAKMIP3	MYADML2	ENSP00000298622	ENSP00000386702	Janus kinase and microtubule interacting protein 3	Myeloid-associated differentiation marker-like protein 2; Myeloid associated differentiation marker like 2	0.646
KCTD19	ARHGEF35	ENSP00000305702	ENSP00000367355	BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19	Rho guanine nucleotide exchange factor 35	0.500
KCTD19	JAKMIP3	ENSP00000305702	ENSP00000298622	BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19	Janus kinase and microtubule interacting protein 3	0.525
KCTD19	MYADML2	ENSP00000305702	ENSP00000386702	BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19	Myeloid-associated differentiation marker-like protein 2; Myeloid associated differentiation marker like 2	0.704
LMF1	ADAP1	ENSP00000262301	ENSP00000442682	Lipase maturation factor 1; Involved in the maturation of specific proteins in the endoplasmic reticulum. Required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway. Each LMF1 molecule chaperones 50 or more molecules of LPL	Arf-GAP with dual PH domain-containing protein 1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4); ArfGAPs	0.703

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