node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD30BL | ANKRD46 | ENSP00000386398 | ENSP00000429015 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | Ankyrin repeat domain-containing protein 46; Ankyrin repeat domain containing | 0.443 |
ANKRD30BL | ANKRD49 | ENSP00000386398 | ENSP00000440396 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | Ankyrin repeat domain-containing protein 49; Induces HBG1 expression. May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF- kappaB pathway (By similarity); Ankyrin repeat domain containing | 0.436 |
ANKRD30BL | FOXI1 | ENSP00000386398 | ENSP00000304286 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | Forkhead box protein I1; Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity); Forkhead boxes | 0.465 |
ANKRD30BL | GABPB1 | ENSP00000386398 | ENSP00000220429 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene; Ankyrin repeat domain containing | 0.436 |
ANKRD30BL | MESP1 | ENSP00000386398 | ENSP00000300057 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | Mesoderm posterior protein 1; Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity); Basic helix-loop-helix proteins | 0.556 |
ANKRD30BL | MESP2 | ENSP00000386398 | ENSP00000342392 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | Mesoderm posterior protein 2; Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together w [...] | 0.448 |
ANKRD30BL | PHACTR2 | ENSP00000386398 | ENSP00000417038 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | Phosphatase and actin regulator 2 | 0.446 |
ANKRD30BL | SF3A3 | ENSP00000386398 | ENSP00000362110 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | Splicing factor 3A subunit 3; Subunit of the splicing factor SF3A required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ’E’ complex; U2 small nucleolar ribonucleoprotein | 0.459 |
ANKRD30BL | SLC6A16 | ENSP00000386398 | ENSP00000338627 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | 0.493 |
ANKRD30BL | TRIM48 | ENSP00000386398 | ENSP00000402414 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | Tripartite motif containing 48; Belongs to the TRIM/RBCC family | 0.541 |
ANKRD46 | ANKRD30BL | ENSP00000429015 | ENSP00000386398 | Ankyrin repeat domain-containing protein 46; Ankyrin repeat domain containing | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | 0.443 |
ANKRD46 | ANKRD49 | ENSP00000429015 | ENSP00000440396 | Ankyrin repeat domain-containing protein 46; Ankyrin repeat domain containing | Ankyrin repeat domain-containing protein 49; Induces HBG1 expression. May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF- kappaB pathway (By similarity); Ankyrin repeat domain containing | 0.494 |
ANKRD49 | ANKRD30BL | ENSP00000440396 | ENSP00000386398 | Ankyrin repeat domain-containing protein 49; Induces HBG1 expression. May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF- kappaB pathway (By similarity); Ankyrin repeat domain containing | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | 0.436 |
ANKRD49 | ANKRD46 | ENSP00000440396 | ENSP00000429015 | Ankyrin repeat domain-containing protein 49; Induces HBG1 expression. May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF- kappaB pathway (By similarity); Ankyrin repeat domain containing | Ankyrin repeat domain-containing protein 46; Ankyrin repeat domain containing | 0.494 |
FOXI1 | ANKRD30BL | ENSP00000304286 | ENSP00000386398 | Forkhead box protein I1; Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity); Forkhead boxes | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | 0.465 |
FOXI1 | MESP1 | ENSP00000304286 | ENSP00000300057 | Forkhead box protein I1; Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity); Forkhead boxes | Mesoderm posterior protein 1; Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity); Basic helix-loop-helix proteins | 0.456 |
GABPB1 | ANKRD30BL | ENSP00000220429 | ENSP00000386398 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene; Ankyrin repeat domain containing | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | 0.436 |
MESP1 | ANKRD30BL | ENSP00000300057 | ENSP00000386398 | Mesoderm posterior protein 1; Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity); Basic helix-loop-helix proteins | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | 0.556 |
MESP1 | FOXI1 | ENSP00000300057 | ENSP00000304286 | Mesoderm posterior protein 1; Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity); Basic helix-loop-helix proteins | Forkhead box protein I1; Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity); Forkhead boxes | 0.456 |
MESP2 | ANKRD30BL | ENSP00000342392 | ENSP00000386398 | Mesoderm posterior protein 2; Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together w [...] | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | 0.448 |