| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CTSH | HMSD | ENSP00000220166 | ENSP00000386207 | Pro-cathepsin H; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | 0.592 |
| HMSD | CTSH | ENSP00000386207 | ENSP00000220166 | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | Pro-cathepsin H; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family | 0.592 |
| HMSD | IL2RG | ENSP00000386207 | ENSP00000363318 | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | Cytokine receptor common subunit gamma; Common subunit for the receptors for a variety of interleukins; CD molecules | 0.643 |
| HMSD | SERPIND1 | ENSP00000386207 | ENSP00000215727 | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner; Belongs to the serpin family | 0.482 |
| HMSD | SERPINE2 | ENSP00000386207 | ENSP00000415786 | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | Glia-derived nexin; Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin; Belongs to the serpin family | 0.504 |
| HMSD | SERPINE3 | ENSP00000386207 | ENSP00000428316 | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | Serpin E3; Probable serine protease inhibitor; Serpin peptidase inhibitors | 0.512 |
| HMSD | SERPINF2 | ENSP00000386207 | ENSP00000321853 | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | Alpha-2-antiplasmin; Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin; Serpin peptidase inhibitors | 0.549 |
| HMSD | SERPING1 | ENSP00000386207 | ENSP00000278407 | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | Plasma protease C1 inhibitor; Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein; Serpin peptidase inhibitors | 0.538 |
| HMSD | SERPINH1 | ENSP00000386207 | ENSP00000434412 | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | Serpin H1; Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen; Serpin peptidase inhibitors | 0.483 |
| HMSD | SERPINI1 | ENSP00000386207 | ENSP00000295777 | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | Neuroserpin; Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (Probable); Serpin peptidase inhibitors | 0.604 |
| HMSD | ZNF419 | ENSP00000386207 | ENSP00000388864 | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | Zinc finger protein 419; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.654 |
| IL2RG | HMSD | ENSP00000363318 | ENSP00000386207 | Cytokine receptor common subunit gamma; Common subunit for the receptors for a variety of interleukins; CD molecules | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | 0.643 |
| SERPIND1 | HMSD | ENSP00000215727 | ENSP00000386207 | Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner; Belongs to the serpin family | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | 0.482 |
| SERPIND1 | SERPINF2 | ENSP00000215727 | ENSP00000321853 | Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner; Belongs to the serpin family | Alpha-2-antiplasmin; Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin; Serpin peptidase inhibitors | 0.471 |
| SERPINE2 | HMSD | ENSP00000415786 | ENSP00000386207 | Glia-derived nexin; Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin; Belongs to the serpin family | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | 0.504 |
| SERPINE3 | HMSD | ENSP00000428316 | ENSP00000386207 | Serpin E3; Probable serine protease inhibitor; Serpin peptidase inhibitors | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | 0.512 |
| SERPINF2 | HMSD | ENSP00000321853 | ENSP00000386207 | Alpha-2-antiplasmin; Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin; Serpin peptidase inhibitors | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | 0.549 |
| SERPINF2 | SERPIND1 | ENSP00000321853 | ENSP00000215727 | Alpha-2-antiplasmin; Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin; Serpin peptidase inhibitors | Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner; Belongs to the serpin family | 0.471 |
| SERPINF2 | SERPING1 | ENSP00000321853 | ENSP00000278407 | Alpha-2-antiplasmin; Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin; Serpin peptidase inhibitors | Plasma protease C1 inhibitor; Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein; Serpin peptidase inhibitors | 0.929 |
| SERPING1 | HMSD | ENSP00000278407 | ENSP00000386207 | Plasma protease C1 inhibitor; Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein; Serpin peptidase inhibitors | Serpin-like protein HMSD; Putative serine protease inhibitor; Minor histocompatibility antigens | 0.538 |
