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STRINGSTRING
ACAA1 ACAA1 PHYH PHYH PEX7 PEX7 HIST1H2BM HIST1H2BM CDHR1 CDHR1 C6orf226 C6orf226 PAQR5 PAQR5 C15orf52 C15orf52 CHRNA4 CHRNA4 CCDC9 CCDC9
"C6orf226" - Uncharacterized protein C6orf226 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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C6orf226Uncharacterized protein C6orf226; Chromosome 6 open reading frame 226 (101 aa)    
Predicted Functional Partners:
ACAA1
3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 (424 aa)
        
      0.859
PEX7
Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import; Belongs to the WD repeat peroxin-7 family (323 aa)
        
      0.799
PHYH
Phytanoyl-CoA dioxygenase, peroxisomal; Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA (338 aa)
        
      0.680
CHRNA4
Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions; Cholinergic receptors nicotinic subunits (627 aa)
            
  0.658
PAQR5
Membrane progestin receptor gamma; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation; Progestin and adipoQ receptor family (330 aa)
            
  0.557
HIST1H2BM
Histone H2B type 1-M; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (126 aa)
            
  0.530
C15orf52
Uncharacterized protein C15orf52; Chromosome 15 open reading frame 52 (534 aa)
            
  0.479
CCDC9
Coiled-coil domain containing 9 (531 aa)
            
  0.476
CDHR1
Cadherin-related family member 1; Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells (By similarity); Cadherin related (859 aa)
            
  0.447
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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